AIMC Topic: Biocompatible Materials

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Self-assembling peptide hydrogels: design, mechanisms, characterization, and biomedical applications.

Soft matter
Self-assembled peptide hydrogels have emerged as a research frontier in biomedical engineering due to their exceptional water-retention capacity and spatiotemporal drug release kinetics. Researchers can fabricate biomaterials with customizable struct...

A soft robotic total artificial hybrid heart.

Nature communications
End-stage heart failure is a deadly disease. Current total artificial hearts (TAHs) carry high mortality and morbidity and offer low quality of life. To overcome current biocompatibility issues, we propose the concept of a soft robotic, hybrid (pumpi...

Hierarchical design of silkworm silk for functional composites.

Chemical Society reviews
Silk-reinforced composites (SRCs) manifest the unique properties of silkworm silk fibers, offering enhanced mechanical strength, biocompatibility, and biodegradability. These composites present an eco-friendly alternative to conventional synthetic ma...

Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach.

Biomaterials
Osteoinduction is an important feature of the next generation of bone repair materials. But the key structural factors and parameters of osteoinductive scaffolds are not yet clarified. This study leverages the efficiency of high-throughput screening ...

Surrogate modeling of electrospun PVA/PLA nanofibers using artificial neural network for biomedical applications.

Scientific reports
Blending poly (lactic acid) (PLA) with poly (vinyl alcohol) (PVA) improves the strength and hydrophilicity of nanofibers, making them suitable for biomedical applications like wound dressings. This study explores how electrospinning parameters-applie...

Ultrasound-activated piezoelectric biomaterials for cartilage regeneration.

Ultrasonics sonochemistry
Due to the low density of chondrocytes and limited ability to repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials to support facial structure, restore fu...

Soft Biological Actuators for Meter-Scale Homeostatic Biohybrid Robots.

Chemical reviews
Skeletal muscle's elegant protein-based architecture powers motion throughout the animal kingdom, with its constituent actomyosin complexes driving intra- and extra-cellular motion. Classical motors and recently developed soft actuators cannot match ...

Evolving biomaterials design from trial and error to intelligent innovation.

Acta biomaterialia
The design and exploration of biomaterials plays a pivotal role in many fields, including medical and engineering. The prevailing approach to biomaterials discovery relies on orthogonal experiments, with repeated attempts to optimize experimental con...

Artificial Intelligence and Multiscale Modeling for Sustainable Biopolymers and Bioinspired Materials.

Advanced materials (Deerfield Beach, Fla.)
Biopolymers and bioinspired materials contribute to the construction of intricate hierarchical structures that exhibit advanced properties. The remarkable toughness and damage tolerance of such multilevel materials are conferred through the hierarchi...

Biocompatible Neuromorphic Device Array Based on Naturally Sourced Mucin for Implantable Bioelectronics.

ACS nano
Although the demand for intelligent implantable bioelectronics is steadily increasing, their progress is hindered by the limited availability of materials with sufficient biocompatibility for implantation. Herein, we propose a neuromorphic device wit...