Genetic redundancy refers to a situation where an individual with a loss-of-function mutation in one gene (single mutant) does not show an apparent phenotype until one or more paralogs are also knocked out (double/higher-order mutant). Previous studi...
MOTIVATION: Identification of functional sites in proteins is essential for functional characterization, variant interpretation and drug design. Several methods are available for predicting either a generic functional site, or specific types of funct...
We propose an extended reservoir computer that shows the functional differentiation of neurons. The reservoir computer is developed to enable changing of the internal reservoir using evolutionary dynamics, and we call it an evolutionary reservoir com...
The problem of the theoretical precariousness of psychology requires defining, at an epistemological level, its concepts and languages and the use of models for finding core concepts and building more or less 'hard' theories. After reviewing some mai...
Collective behaviors by self-organization are ubiquitous in nature and human society and extensive efforts have been made to explore the mechanisms behind them. Artificial intelligence (AI) as a rapidly developing field is of great potential for thes...
Evolution is a blind fitting process by which organisms become adapted to their environment. Does the brain use similar brute-force fitting processes to learn how to perceive and act upon the world? Recent advances in artificial neural networks have ...
Modeling discrete phenotypic traits for either ancestral character state reconstruction or morphology-based phylogenetic inference suffers from ambiguities of character coding, homology assessment, dependencies, and selection of adequate models. Thes...
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Jun 10, 2019
Reservoir computing (RC) is a powerful computational paradigm that allows high versatility with cheap learning. While other artificial intelligence approaches need exhaustive resources to specify their inner workings, RC is based on a reservoir with ...
Documented occurrences of fossil taxa are the empirical foundation for understanding large-scale biodiversity changes and evolutionary dynamics in deep time. The fossil record contains vast amounts of understudied taxa. Yet the compilation of huge vo...
Rather than acting as a review or analysis of the field, this essay focuses squarely on the motivations for investigating open-endedness and the opportunities it opens up. It begins by contemplating the awesome accomplishments of evolution in nature ...