AIMC Topic: Biological Ontologies

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An ontology-based tool for modeling and documenting events in neurosurgery.

BMC medical informatics and decision making
BACKGROUND: Intraoperative neurophysiological monitoring (IOM) plays a pivotal role in enhancing patient safety during neurosurgical procedures. This vital technique involves the continuous measurement of evoked potentials to provide early warnings a...

Predicting Future Disorders via Temporal Knowledge Graphs and Medical Ontologies.

IEEE journal of biomedical and health informatics
Despite the vast potential for insights and value present in Electronic Health Records (EHRs), it is challenging to fully leverage all the available information, particularly that contained in the free-text data written by clinicians describing the h...

Empowering standardization of cancer vaccines through ontology: enhanced modeling and data analysis.

Journal of biomedical semantics
BACKGROUND: The exploration of cancer vaccines has yielded a multitude of studies, resulting in a diverse collection of information. The heterogeneity of cancer vaccine data significantly impedes effective integration and analysis. While CanVaxKB ser...

Report of the HIMSS-SIIM Enterprise Imaging Community Data Standards Evaluation Workgroup: Anatomic Ontology Assessment.

Journal of imaging informatics in medicine
Previously, the lack of a standard body part ontology has been identified as a critical deficiency needed to enable enterprise imaging. This whitepaper aims to provide a comprehensive assessment of anatomical ontologies with the aim of facilitating e...

On the relationship between scientific theory and ontology in everything flows.

History and philosophy of the life sciences
In their anthology Everything Flows: Towards a Processual Philosophy of Biology, Daniel J. Nicholson and John Dupré argue that modern theories of biology imply that the fundamental structure of reality is processual at its core. In the present work, ...

Homeostasis imbalance process ontology: a study on COVID-19 infectious processes.

BMC medical informatics and decision making
BACKGROUND: One significant challenge in addressing the coronavirus disease 2019 (COVID-19) pandemic is to grasp a comprehensive picture of its infectious mechanisms. We urgently need a consistent framework to capture the intricacies of its complicat...

MRIO: the Magnetic Resonance Imaging Acquisition and Analysis Ontology.

Neuroinformatics
Magnetic resonance imaging of the brain is a useful tool in both the clinic and research settings, aiding in the diagnosis and treatments of neurological disease and expanding our knowledge of the brain. However, there are many challenges inherent in...

Ontological representation, modeling, and analysis of parasite vaccines.

Journal of biomedical semantics
BACKGROUND: Pathogenic parasites are responsible for multiple diseases, such as malaria and Chagas disease, in humans and livestock. Traditionally, pathogenic parasites have been largely an evasive topic for vaccine design, with most successful vacci...

Bayesian-knowledge driven ontologies: A framework for fusion of semantic knowledge under uncertainty and incompleteness.

PloS one
The modeling of uncertain information is an open problem in ontology research and is a theoretical obstacle to creating a truly semantic web. Currently, ontologies often do not model uncertainty, so stochastic subject matter must either be normalized...