AI Medical Compendium Topic:
Biological Ontologies

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Harmonizing SNOMED CT with BioTopLite: An Exercise in Principled Ontology Alignment.

Studies in health technology and informatics
The integration of heterogeneous ontologies is often hampered by different upper level categories and relations. We report on an on-going effort to align clinical terminology/ontology SNOMED CT with the formal upper-level ontology BioTopLite. This al...

A Process for the Representation of openEHR ADL Archetypes in OWL Ontologies.

Studies in health technology and informatics
ADL is a formal language to express archetypes, independent of standards or domain. However, its specification is not precise enough in relation to the specialization and semantic of archetypes, presenting difficulties in implementation and a few ava...

Named Entity Recognition in Chinese Clinical Text Using Deep Neural Network.

Studies in health technology and informatics
Rapid growth in electronic health records (EHRs) use has led to an unprecedented expansion of available clinical data in electronic formats. However, much of the important healthcare information is locked in the narrative documents. Therefore Natural...

Recruit--An Ontology Based Information Retrieval System for Clinical Trials Recruitment.

Studies in health technology and informatics
Clinical trials are studies designed to assess whether a new intervention is better than the current alternatives. However, most of them fail to recruit participants on schedule. It is hard to use Electronic Health Record (EHR) data to find eligible ...

An Ontology-Based Clinical Decision Support System for the Management of Patients with Multiple Chronic Disorders.

Studies in health technology and informatics
Decision support systems, as means of disseminating clinical practice guidelines, are powerful software that may lead to an improvement of medical practices. However, they are not always efficient and may suffer from limitations among which are lack ...

On Building an Ontological Knowledge Base for Managing Patient Safety Events.

Studies in health technology and informatics
Over the past decade, improving healthcare quality and safety through patient safety event reporting systems has drawn much attention. Unfortunately, such systems are suffering from low data quality, inefficient data entry and ineffective information...

An efficient algorithm for updating regular expression indexes in RDF databases.

International journal of data mining and bioinformatics
The Resource Description Framework (RDF) is widely used for sharing biomedical data, such as gene ontology or the online protein database UniProt. SPARQL is a native query language for RDF, featuring regular expressions in queries for which exact val...

Ontogenic retinal changes in three ecologically distinct elopomorph fishes (Elopomorpha:Teleostei) correlate with light environment and behavior.

Visual neuroscience
Unlike the mammalian retina, the teleost fish retina undergoes persistent neurogenesis from intrinsic stem cells. In marine teleosts, most cone photoreceptor genesis occurs early in the embryonic and larval stages, and rods are added primarily during...

Semi-automated evaluation of biomedical ontologies for the biobanking domain based on competency questions.

Studies in health technology and informatics
BACKGROUND: Biosample collections and biobank information systems have become a key enabler for medical research. Therefore it is important to identify potentially relevant ontologies to semantically enrich information related to the biobanking domai...