The BBB remains a major obstacle to effective treatment of CNS disorders by limiting the entry of most therapeutics into the brain. The hCMEC/D3 is widely used as anin vitromodel to study BBB structure, permeability, and drug transport. In parallel, ...
Advanced three-dimensional (3D) tissue models that recapitulate autoimmune disease progression can enable mechanistic studies and accelerate the development of targeted therapies with reduced reliance on systemic immunosuppression. Here, we present a...
3D bioprinting enables rapid fabrication of complex biological structures for tissue engineering applications. However, optimizing bioink formulation remains challenging due to complex relationships among material properties, printability, and cell v...
Alginate-based biomaterials have been widely used for tissue repair and regeneration, owing to their tunability, biocompatibility, biodegradability, and low cytotoxicity. With the rapid advancement of bioprinting technology, alginate has increasingly...
Recent advances in green nanomaterials have primarily focused on mitigating toxicity through passive approaches, yet emerging technologies suggest a transformative paradigm shift toward programmable nanomaterials with dynamic biointerfaces. This Revi...
Recent advances in cancer research emphasize the development of physiologically relevant models to better understand tumor behavior and therapeutic responses. The tumor microenvironment (TME) plays a pivotal role in tumor progression, metastasis, and...
Journal of controlled release : official journal of the Controlled Release Society
Sep 10, 2025
As three-dimensional (3D), physiologically relevant models, organoids are rapidly becoming revolutionary platforms in biomedical research. With their ability to recapitulate tissue architecture, disease heterogeneity, and patient-specific therapeutic...
Theranostic hydrogels represent a groundbreaking approach by integrating therapeutic and diagnostic capabilities within a single platform, enabling real-time monitoring of wounds and precise treatment applications. These advanced materials are engine...
International journal of pharmaceutics
Jul 5, 2025
Lab-on-a-chip (LoC) technologies have emerged as transformative tools in cancer research, particularly in evaluating drug resistance, which remains a significant barrier to effective treatment. These miniaturized platforms allow for the integration o...
Bioprinting is a promising family of processes combining 3D printing with life sciences, offering the potential to significantly advance various applications. Despite numerous research efforts aimed at enhancing process modeling, optimizing capabilit...
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