AIMC Topic: Bioreactors
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Estimation of fungal biomass using multiphase artificial neural network based dynamic soft sensor.
Journal of microbiological methods
Feb 5, 2019
Interest in low cost cellulase production has become a major challenge in recent years for biorefineries. Fed-batch fermentation of Trichoderma strains for the production of low cost cellulase is carried out on complex media that has various soluble ...
Application of recurrent neural network for online prediction of cell density of recombinant Pichia pastoris producing HBsAg.
Preparative biochemistry & biotechnology
Feb 1, 2019
Artificial neural networking (ANN) seems to be a promising soft sensor for implementing current approaches of quality by design (QbD) and process analytical technologies (PAT) in the biopharmaceutical industry. In this study, we aimed to implement be...
Co-digestion of Laminaria digitata with cattle manure: A unimodel simulation study of both batch and continuous experiments.
Bioresource technology
Dec 31, 2018
This work investigated the thermophilic (55 °C) co-digestion performance both in batch and continuous mode operation. The biochemical methane potentials of L. digitata and cattle manure were 308 ± 24 and 203 ± 33 mL CH/g VS, respectively. The optimum...
Functional expression of porcine interferon-α using a combinational strategy in Pichia pastoris GS115.
Enzyme and microbial technology
Dec 10, 2018
Porcine interferon-α (pIFN-α) could be used as the vaccine adjuvant to enhance the antiviral ability of porcine in swine industry. In here, a combinational strategy integrating codon optimization, multiple gene insertion, strong AOX1 promoter, and ef...
The key role of inoculated sludge in fast start-up of sequencing batch reactor for the domestication of aerobic granular sludge.
Journal of environmental sciences (China)
Sep 7, 2018
Two types of inoculated sludges, granular sludge that had been stored at -20°C and activated sludge, were investigated for the domestication of aerobic granular sludges (AGSs) in sequencing batch reactors (SBRs). The results showed that using the sto...
Evaluation and optimization of anammox baffled reactor (AnBR) by artificial neural network modeling and economic analysis.
Bioresource technology
Sep 4, 2018
Anammox baffled reactor (AnBR) had a moderate start-up period of 53 days. Interestingly, tangled relationships between key parameters affecting anammox performance were observed, i.e., polynomial function for nitrogen loading rate (NLR) with extracel...
Enrichment of thermophilic and mesophilic microbial consortia for efficient degradation of corn stalk.
Journal of environmental sciences (China)
Jul 29, 2018
Six different environmental samples were applied to enrich microbial consortia for efficient degradation of corn stalk, under the thermophilic and mesophilic conditions. The consortium obtained from anaerobic digested sludge under thermophilic condit...
Leveraging knowledge engineering and machine learning for microbial bio-manufacturing.
Biotechnology advances
May 3, 2018
Genome scale modeling (GSM) predicts the performance of microbial workhorses and helps identify beneficial gene targets. GSM integrated with intracellular flux dynamics, omics, and thermodynamics have shown remarkable progress in both elucidating com...
Feedforward neural network model estimating pollutant removal process within mesophilic upflow anaerobic sludge blanket bioreactor treating industrial starch processing wastewater.
Bioresource technology
Feb 20, 2018
In this a, three-layered feedforward-backpropagation artificial neural network (BPANN) model was developed and employed to evaluate COD removal an upflow anaerobic sludge blanket (UASB) reactor treating industrial starch processing wastewater. At the...
Employing response surface methodology (RSM) to improve methane production from cotton stalk.
Environmental science and pollution research international
Dec 28, 2017
China is the largest cotton producer with the cotton output accounting for 25% of the total world's cotton production. A large quantity of cotton stalk (CS) waste is generated which is burned and causes environmental and ecological problems. This stu...
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