AIMC Topic: Birefringence

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Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning.

Nature communications Sep 12, 2024
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues, leading to progressive organ dysfunction and failure. Congo red is the gold-standard chemical stain for visualizing amyloid deposits in tissue, showing birefringenc...
Humans Deep Learning Staining and Labeling Myocardium Microscopy, Fluorescence Amyloid Amyloidosis Optical Imaging Congo Red Plaque, Amyloid Birefringence Microscopy, Polarization
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Detecting central fixation by means of artificial neural networks in a pediatric vision screener using retinal birefringence scanning.

Biomedical engineering online Apr 27, 2017
BACKGROUND: Reliable detection of central fixation and eye alignment is essential in the diagnosis of amblyopia ("lazy eye"), which can lead to blindness. Our lab has developed and reported earlier a pediatric vision screener that performs scanning o...
Humans Neural Networks, Computer Reproducibility of Results Young Adult Adult Sensitivity and Specificity Male Diagnosis, Computer-Assisted Adolescent Child, Preschool Child Refractometry Fixation, Ocular Retinoscopy Amblyopia Birefringence Vision Screening
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