AIMC Topic: Refractometry

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Predictive modeling of hemoglobin refractive index using Gaussian process regression with interpretability through partial dependence plots.

PloS one May 30, 2025
Accurately predicting the refractive index of hemoglobin across various wavelengths and concentrations is critical for advancing optical diagnostic techniques in biological and clinical applications. This study introduces a predictive model based on ...
Regression Analysis Hemoglobins Normal Distribution Refractometry Humans
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Discrimination of wheat gluten quality utilizing terahertz time-domain spectroscopy (THz-TDS).

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Nov 17, 2024
Wheat is an important food crop in the world, and wheat gluten quality is one of the important standards for judging the use of wheat. In this study, a combination of chemometric and machine learning methods based on THz-TDS were used to identify thr...
Support Vector Machine Triticum Glutens Neural Networks, Computer Algorithms Refractometry Terahertz Spectroscopy
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Convolutional neural network-based regression analysis to predict subnuclear chromatin organization from two-dimensional optical scattering signals.

Journal of biomedical optics Aug 28, 2024
SIGNIFICANCE: Azimuth-resolved optical scattering signals obtained from cell nuclei are sensitive to changes in their internal refractive index profile. These two-dimensional signals can therefore offer significant insights into chromatin organizatio...
Chromatin Neural Networks, Computer Machine Learning Humans Algorithms Scattering, Radiation Regression Analysis Refractometry Cell Nucleus
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Deep learning based analysis of microstructured materials for thermal radiation control.

Scientific reports Jun 13, 2022
Microstructured materials that can selectively control the optical properties are crucial for the development of thermal management systems in aerospace and space applications. However, due to the vast design space available for microstructures with ...
Deep Learning Refractometry Neural Networks, Computer Machine Learning Temperature
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Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning.

Nature cell biology Dec 7, 2021
Simultaneous imaging of various facets of intact biological systems across multiple spatiotemporal scales is a long-standing goal in biology and medicine, for which progress is hindered by limits of conventional imaging modalities. Here we propose us...
Cell Nucleus Actins Cell Membrane HeLa Cells 3T3 Cells HEK293 Cells Subcellular Fractions Electron Microscope Tomography COS Cells Lipid Droplets Optical Imaging Refractometry Cell Nucleolus Cell Line, Tumor Single-Cell Analysis Imaging, Three-Dimensional Mice Mitochondria Chlorocebus aethiops Humans Animals Deep Learning
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Mathematical and computational modeling for the determination of optical parameters of breast cancer cell.

Electromagnetic biology and medicine Jul 29, 2021
This study enumerates the quantitative measurement of optical parameters used in several diagnostic procedures for malignant tissue. Optical diagnosis is proposed due to its non-invasive and non-destructive nature. This paper recapitulates Fresnel eq...
Female Breast Neoplasms Refractometry Artificial Intelligence Computer Simulation Humans
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Photonic Crystal Fiber-Based Reconfigurable Biosensor Using Phase Change Material.

IEEE transactions on nanobioscience Jun 30, 2021
A reconfigurable biosensor with different spectral sensitivities could provide new opportunities to increase the label-free selectivity and sensitivity for biomolecules. Here, we propose and numerically demonstrate a phase change chalcogenide materia...
Biosensing Techniques Optics and Photonics Artificial Intelligence Refractometry Photons
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Macular Ganglion Cell-Inner Plexiform Layer Thickness Prediction from Red-free Fundus Photography using Hybrid Deep Learning Model.

Scientific reports Feb 24, 2020
We developed a hybrid deep learning model (HDLM) algorithm that quantitatively predicts macular ganglion cell-inner plexiform layer (mGCIPL) thickness from red-free retinal nerve fiber layer photographs (RNFLPs). A total of 789 pairs of RNFLPs and sp...
Diagnosis, Computer-Assisted Deep Learning ROC Curve Optic Nerve Tomography, Optical Coherence Humans Support Vector Machine Diagnostic Techniques, Ophthalmological Regression Analysis Female Male Fundus Oculi Refractometry Aged Adult Middle Aged Translational Research, Biomedical Glaucoma Aged, 80 and over Sensitivity and Specificity Case-Control Studies Algorithms Retinal Ganglion Cells Young Adult Intraocular Pressure Retrospective Studies
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Estimating the refractive index of oxygenated and deoxygenated hemoglobin using genetic algorithm - support vector regression model.

Computer methods and programs in biomedicine May 21, 2018
BACKGROUND AND OBJECTIVES: The refractive index of hemoglobin plays important role in hematology due to its strong correlation with the pathophysiology of different diseases. Measurement of the real part of the refractive index remains a challenge du...
Hemoglobins Support Vector Machine Humans Refractometry Software Models, Statistical Oxygen Algorithms Reproducibility of Results
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Predicting of the refractive index of haemoglobin using the Hybrid GA-SVR approach.

Computers in biology and medicine Apr 30, 2018
The optical properties of blood play crucial roles in medical diagnostics and treatment, and in the design of new medical devices. Haemoglobin is a vital constituent of the blood whose optical properties affect all of the optical properties of human ...
Hemoglobins Refractometry Humans Support Vector Machine Algorithms Regression Analysis Databases, Factual Models, Biological
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