AIMC Topic: Microscopy, Polarization

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Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning.

Nature communications Sep 12, 2024
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues, leading to progressive organ dysfunction and failure. Congo red is the gold-standard chemical stain for visualizing amyloid deposits in tissue, showing birefringenc...
Humans Deep Learning Staining and Labeling Myocardium Microscopy, Fluorescence Amyloid Amyloidosis Optical Imaging Congo Red Plaque, Amyloid Birefringence Microscopy, Polarization
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Characterization and classification of ductal carcinoma tissue using four channel based stokes-mueller polarimetry and machine learning.

Lasers in medical science May 4, 2024
Interaction of polarized light with healthy and abnormal regions of tissue reveals structural information associated with its pathological condition. Even a slight variation in structural alignment can induce a change in polarization property, which ...
Humans Machine Learning Female Breast Neoplasms Image Processing, Computer-Assisted Support Vector Machine Carcinoma, Ductal, Breast Microscopy, Polarization
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Computationally Enabled Polychromatic Polarized Imaging Enables Mapping of Matrix Architectures that Promote Pancreatic Ductal Adenocarcinoma Dissemination.

The American journal of pathology Jul 1, 2025
Pancreatic ductal adenocarcinoma (PDA) is a highly metastatic and lethal disease. In PDA, extracellular matrix (ECM) architectures, known as tumor-associated collagen signatures (TACSs), regulate invasion and metastatic spread in both early dissemina...
Humans Image Processing, Computer-Assisted Pancreatic Neoplasms Carcinoma, Pancreatic Ductal Collagen Extracellular Matrix Microscopy, Polarization
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Classification of marine microalgae using low-resolution Mueller matrix images and convolutional neural network.

Applied optics Nov 1, 2020
In this paper, we used a convolutional neural network to study the classification of marine microalgae by using low-resolution Mueller matrix images. Mueller matrix images of 12 species of algae from 5 families were measured by a Mueller matrix micro...
Neural Networks, Computer Algorithms Light Image Interpretation, Computer-Assisted Microalgae Optical Imaging Microscopy, Polarization
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