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Brain Ischemia

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Interpretable deep learning for the prognosis of long-term functional outcome post-stroke using acute diffusion weighted imaging.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Advances in deep learning can be applied to acute stroke imaging to build powerful and explainable prediction models that could supersede traditionally used biomarkers. We aimed to evaluate the performance and interpretability of a deep learning mode...

Image level detection of large vessel occlusion on 4D-CTA perfusion data using deep learning in acute stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVES: Automated image-level detection of large vessel occlusions (LVO) could expedite patient triage for mechanical thrombectomy. A few studies have previously attempted LVO detection using artificial intelligence (AI) on CT angiography (CTA) i...

Identifying acute ischemic stroke patients within the thrombolytic treatment window using deep learning.

Journal of neuroimaging : official journal of the American Society of Neuroimaging
BACKGROUND AND PURPOSE: Treatment of acute ischemic stroke is heavily contingent upon time, as there is a strong relationship between time clock and tissue progression. Work has established imaging biomarker assessments as surrogates for time since s...

Deep learning-based behavioral profiling of rodent stroke recovery.

BMC biology
BACKGROUND: Stroke research heavily relies on rodent behavior when assessing underlying disease mechanisms and treatment efficacy. Although functional motor recovery is considered the primary targeted outcome, tests in rodents are still poorly reprod...

Automated estimation of ischemic core volume on noncontrast-enhanced CT via machine learning.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
BACKGROUND: Accurate estimation of ischemic core on baseline imaging has treatment implications in patients with acute ischemic stroke (AIS). Machine learning (ML) algorithms have shown promising results in estimating ischemic core using routine nonc...

Predicting Hypoperfusion Lesion and Target Mismatch in Stroke from Diffusion-weighted MRI Using Deep Learning.

Radiology
Background Perfusion imaging is important to identify a target mismatch in stroke but requires contrast agents and postprocessing software. Purpose To use a deep learning model to predict the hypoperfusion lesion in stroke and identify patients with ...

Deep learning-based personalised outcome prediction after acute ischaemic stroke.

Journal of neurology, neurosurgery, and psychiatry
BACKGROUND: Whether deep learning models using clinical data and brain imaging can predict the long-term risk of major adverse cerebro/cardiovascular events (MACE) after acute ischaemic stroke (AIS) at the individual level has not yet been studied.

Deep learning for collateral evaluation in ischemic stroke with imbalanced data.

International journal of computer assisted radiology and surgery
PURPOSE: Collateral evaluation is typically done using visual inspection of cerebral images and thus suffers from intra- and inter-rater variability. Large open databases of ischemic stroke patients are rare, limiting the use of deep learning methods...

DEEP MOVEMENT: Deep learning of movie files for management of endovascular thrombectomy.

European radiology
OBJECTIVES: Treatment and outcomes of acute stroke have been revolutionised by mechanical thrombectomy. Deep learning has shown great promise in diagnostics but applications in video and interventional radiology lag behind. We aimed to develop a mode...

Using Deep-Learning-Based Artificial Intelligence Technique to Automatically Evaluate the Collateral Status of Multiphase CTA in Acute Ischemic Stroke.

Tomography (Ann Arbor, Mich.)
BACKGROUND: Collateral status is an important predictor for the outcome of acute ischemic stroke with large vessel occlusion. Multiphase computed-tomography angiography (mCTA) is useful to evaluate the collateral status, but visual evaluation of this...