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Thrombosis

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Mapping Thrombosis Serum Markers by H-NMR Allied with Machine Learning Tools.

Molecules (Basel, Switzerland)
Machine learning and artificial intelligence tools were used to investigate the discriminatory potential of blood serum metabolites for thromboembolism and antiphospholipid syndrome (APS). H-NMR-based metabonomics data of the serum samples of patient...

Programmable ultrasound-mediated swarms manipulation of bacteria-red blood cell microrobots for tumor-specific thrombosis and robust photothermal therapy.

Trends in biotechnology
Despite the excellent advantages of biomicrorobots, such as autonomous navigation and targeting actuation, effective penetration and retention to deep lesion sites for effective therapy remains a longstanding challenge. Here, we present dual-engine c...

Residual risk prediction in anticoagulated patients with atrial fibrillation using machine learning: A report from the GLORIA-AF registry phase II/III.

European journal of clinical investigation
BACKGROUND: Although oral anticoagulation decreases the risk of thromboembolism in patients with atrial fibrillation (AF), a residual risk of thrombotic events still exists. This study aimed to construct machine learning (ML) models to predict the re...

Development and validation of machine learning-based prediction model for central venous access device-related thrombosis in children.

Thrombosis research
BACKGROUND: Identifying independent risk factors and implementing high-quality assessment tools for early detection of patients at high risk of central venous access device (CVAD)-related thrombosis (CRT) plays a critical role in delivering timely pr...

Development and validation of an interpretable machine learning model for predicting left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients.

PloS one
PURPOSE: Left atrial thrombus or spontaneous echo contrast (LAT/SEC) are widely recognized as significant contributors to cardiogenic embolism in non-valvular atrial fibrillation (NVAF). This study aimed to construct and validate an interpretable pre...

Enhancing prediction and stratifying risk: machine learning and bayesian-learning models for catheter-related thrombosis in chemotherapy patients.

BMC cancer
BACKGROUND: Catheter-related thrombosis (CRT) is a serious complication in cancer patients undergoing chemotherapy, yet existing risk prediction models demonstrate limited accuracy. This study aimed to evaluate the clinical utility of machine learnin...

Construction and validation of a predictive model for intracardiac thrombus risk in patients with dilated cardiomyopathy: a retrospective study.

BMC cardiovascular disorders
BACKGROUND: Systemic embolic events due to exfoliation of intracardiac thrombus (ICT) are one of the catastrophic complications of dilated cardiomyopathy (DCM). This study intended to develop a prediction model to predict the risk of ICT in patients ...

Sensing the Future of Thrombosis Management: Integrating Vessel-on-a-Chip Models, Advanced Biosensors, and AI-Driven Digital Twins.

ACS sensors
Thrombotic events, such as strokes and deep vein thrombosis, remain a significant global health burden, with traditional diagnostic methods often failing to capture the complex, patient-specific nuances of thrombosis risk. This Perspective explores t...

Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Micro/nano-scale robotic devices are emerging as a cutting-edge approach for precision intravascular therapies, offering the potential for highly targeted drug delivery. While employing micro/nanorobotics for stroke treatment is a promising strategy ...

Comprehensive quality evaluation of crude material of Ligusticum chuanxiong Hort. through high performance liquid chromatography coupled with DenseNet-121 assisted hyperspectral imaging and anti-thrombotic zebrafish bioassay.

Journal of pharmaceutical and biomedical analysis
An innovative, integrated strategy was developed for rapid and comprehensive quality assessment of Ligusticum chuanxiong Hort., the key raw material for Guanxinning tablets. This approach simultaneously evaluates both chemical composition and biologi...