AIMC Topic: Clathrin
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Deep neural network automated segmentation of cellular structures in volume electron microscopy.
The Journal of cell biology
Dec 5, 2022
Volume electron microscopy is an important imaging modality in contemporary cell biology. Identification of intracellular structures is a laborious process limiting the effective use of this potentially powerful tool. We resolved this bottleneck with...
DeepCLA: A Hybrid Deep Learning Approach for the Identification of Clathrin.
Journal of chemical information and modeling
Dec 21, 2020
Clathrin is a highly evolutionarily conserved protein, which can affect membrane cleavage and membrane release of vesicles. The absence of clathrin in the cellular system affects a variety of human diseases. Effective recognition of clathrin plays an...
Identification of clathrin proteins by incorporating hyperparameter optimization in deep learning and PSSM profiles.
Computer methods and programs in biomedicine
May 17, 2019
BACKGROUND AND OBJECTIVES: Clathrin is an adaptor protein that serves as the principal element of the vesicle-coating complex and is important for the membrane cleavage to dispense the invaginated vesicle from the plasma membrane. The functional loss...
Machine-Learning-Based Analysis in Genome-Edited Cells Reveals the Efficiency of Clathrin-Mediated Endocytosis.
Cell reports
Sep 17, 2015
Cells internalize various molecules through clathrin-mediated endocytosis (CME). Previous live-cell imaging studies suggested that CME is inefficient, with about half of the events terminated. These CME efficiency estimates may have been confounded b...
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