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Mammary Glands, Human

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Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to .

Frontiers in cellular and infection microbiology
() is problematic for lactating mammals and public health. Understanding of mechanisms by which the hosts respond to severe invasion of remains elusive. In this study, the genome-wide expression of mRNAs and miRNAs in bovine mammary gland cells wer...

Machine-Learning-Based Analysis in Genome-Edited Cells Reveals the Efficiency of Clathrin-Mediated Endocytosis.

Cell reports
Cells internalize various molecules through clathrin-mediated endocytosis (CME). Previous live-cell imaging studies suggested that CME is inefficient, with about half of the events terminated. These CME efficiency estimates may have been confounded b...

Estimation of glandular dose in mammography based on artificial neural networks.

Physics in medicine and biology
This work proposes using artificial neural networks (ANNs) for the regression of the dosimetric quantities employed in mammography. The data were generated by Monte Carlo (MC) simulations using a modified and validated version of the PENELOPE (v. 201...

Prospective Analysis Using a Novel CNN Algorithm to Distinguish Atypical Ductal Hyperplasia From Ductal Carcinoma in Situ in Breast.

Clinical breast cancer
INTRODUCTION: We previously developed a convolutional neural networks (CNN)-based algorithm to distinguish atypical ductal hyperplasia (ADH) from ductal carcinoma in situ (DCIS) using a mammographic dataset. The purpose of this study is to further va...

Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning.

PLoS computational biology
Phenotypic profiling of large three-dimensional microscopy data sets has not been widely adopted due to the challenges posed by cell segmentation and feature selection. The computational demands of automated processing further limit analysis of hard-...

Automated Breast Density Assessment for Full-Field Digital Mammography and Digital Breast Tomosynthesis.

Cancer prevention research (Philadelphia, Pa.)
Mammographic density is a strong risk factor for breast cancer and is reported clinically as part of Breast Imaging Reporting and Data System (BI-RADS) results issued by radiologists. Automated assessment of density is needed that can be used for bot...