Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2024
The quickly-expanding nature of published medical literature makes it challenging for clinicians and researchers to keep up with and summarize recent, relevant findings in a timely manner. While several closed-source summarization tools based on larg...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2024
Artificial Intelligence (AI) models are substantially enhancing the capability to analyze complex and multi-dimensional datasets. Generative AI and deep learning models have demonstrated significant advancements in extracting knowledge from unstructu...
Endocrine, metabolic & immune disorders drug targets
Jan 1, 2024
OBJECTIVE: To investigate and validate ferroptosis genes (FRGs) in ulcerative colitis (UC) for diagnostic, subtype, and biological agent reactivity, with the goal of providing a foundation for the identification of novel therapeutic targets and the r...
The protein folding mechanisms are crucial to understanding the fundamental processes of life and solving many biological and medical problems. By studying the folding process, we can reveal how proteins achieve their biological functions through spe...
Combinatorial chemistry & high throughput screening
Jan 1, 2024
BACKGROUND: To elucidate the detailed mechanisms of citrullination at the molecular level and design drugs applicable to major human diseases, predicting protein citrullination sites (PCSs) is essential. Using experimental approaches to predict PCSs ...
Proteins have been playing a critical role in the regulation of diverse biological processes related to human life. With the increasing demand, functional proteins are sparse in this immense sequence space. Therefore, protein design has become an imp...
MOTIVATION: There is mounting evidence that the subcellular localization of lncRNAs can provide valuable insights into their biological functions. In the real world of transcriptomes, lncRNAs are usually localized in multiple subcellular localization...
Omics : a journal of integrative biology
Dec 1, 2023
With climate emergency, COVID-19, and the rise of planetary health scholarship, the binary of human and ecosystem health has been deeply challenged. The interdependence of human and nonhuman animal health is increasingly acknowledged and paving the w...
Model quality evaluation is a crucial part of protein structural biology. How to distinguish high-quality models from low-quality models, and to assess which high-quality models have relatively incorrect regions for improvement, are remain a challeng...
Subcellular localizations of ncRNAs are associated with specific functions. Currently, an increasing number of biological researchers are focusing on computational approaches to identify subcellular localizations of ncRNAs. However, the performance o...
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