AIMC Topic: Connectome

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Sparse Scanning Electron Microscopy Data Acquisition and Deep Neural Networks for Automated Segmentation in Connectomics.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
With the growing importance of three-dimensional and very large field of view imaging, acquisition time becomes a serious bottleneck. Additionally, dose reduction is of importance when imaging material like biological tissue that is sensitive to elec...

Functional, Anatomical, and Morphological Networks Highlight the Role of Basal Ganglia-Thalamus-Cortex Circuits in Schizophrenia.

Schizophrenia bulletin
Evidence from electrophysiological, functional, and structural research suggests that abnormal brain connectivity plays an important role in the pathophysiology of schizophrenia. However, most previous studies have focused on single modalities only, ...

Connectome-based individualized prediction of loneliness.

Social cognitive and affective neuroscience
Loneliness is an increasingly prevalent condition linking with enhanced morbidity and premature mortality. Despite recent proposal on medicalization of loneliness, so far no effort has been made to establish a model capable of predicting loneliness a...

Imaging Connectomics and the Understanding of Brain Diseases.

Advances in experimental medicine and biology
Neuroimaging-based personalized medicine is emerging to characterize brain disorders and their evolution at the patient level. In this chapter, we present the most classic methods used to infer large-scale brain connectivity based on functional MRI. ...

Disease Definition for Schizophrenia by Functional Connectivity Using Radiomics Strategy.

Schizophrenia bulletin
Specific biomarker reflecting neurobiological substrates of schizophrenia (SZ) is required for its diagnosis and treatment selection of SZ. Evidence from neuroimaging has implicated disrupted functional connectivity in the pathophysiology. We aimed t...

Distributed Intrinsic Functional Connectivity Patterns Predict Diagnostic Status in Large Autism Cohort.

Brain connectivity
Diagnosis of autism spectrum disorder (ASD) currently relies on behavioral observations because brain markers are unknown. Machine learning approaches can identify patterns in imaging data that predict diagnostic status, but most studies using functi...

Classifying Schizophrenia Using Multimodal Multivariate Pattern Recognition Analysis: Evaluating the Impact of Individual Clinical Profiles on the Neurodiagnostic Performance.

Schizophrenia bulletin
Previous studies have shown that structural brain changes are among the best-studied candidate markers for schizophrenia (SZ) along with functional connectivity (FC) alterations of resting-state (RS) patterns. This study aimed to investigate effects ...