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Cyclic Nucleotide Phosphodiesterases, Type 2

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Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-B/p65 Signaling in Chronic Radiculitis Rats.

Pain research & management 30651902
BACKGROUND: Oxygen/ozone therapy is a minimally invasive technique for the treatment of radiculitis from lumbar disc herniation. This study aimed at investigating whether intrathecal administration of low-concentration oxygen/ozone could attenuate ch...
Animals Cyclic AMP Cyclic GMP Cyclic Nucleotide Phosphodiesterases, Type 2 Disease Models, Animal Hyperalgesia Intervertebral Disc Displacement Male NF-kappa B Oxygen Ozone Radiculopathy Rats Rats, Wistar Signal Transduction Transcription Factor RelA Treatment Outcome
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