AIMC Topic: Datasets as Topic

Clear Filters Showing 901 to 910 of 1098 articles

NetSurfP-3.0: accurate and fast prediction of protein structural features by protein language models and deep learning.

Nucleic acids research
Recent advances in machine learning and natural language processing have made it possible to profoundly advance our ability to accurately predict protein structures and their functions. While such improvements are significantly impacting the fields o...

The derivation of an International Classification of Diseases, Tenth Revision-based trauma-related mortality model using machine learning.

The journal of trauma and acute care surgery
BACKGROUND: Existing mortality prediction models have attempted to quantify injury burden following trauma-related admissions with the most notable being the Injury Severity Score (ISS). Although easy to calculate, it requires additional administrati...

Organism-specific training improves performance of linear B-cell epitope prediction.

Bioinformatics (Oxford, England)
MOTIVATION: In silico identification of linear B-cell epitopes represents an important step in the development of diagnostic tests and vaccine candidates, by providing potential high-probability targets for experimental investigation. Current predict...

Comparative evaluation of shape retrieval methods on macromolecular surfaces: an application of computer vision methods in structural bioinformatics.

Bioinformatics (Oxford, England)
MOTIVATION: The investigation of the structure of biological systems at the molecular level gives insights about their functions and dynamics. Shape and surface of biomolecules are fundamental to molecular recognition events. Characterizing their geo...

Comparative analysis of molecular fingerprints in prediction of drug combination effects.

Briefings in bioinformatics
Application of machine and deep learning methods in drug discovery and cancer research has gained a considerable amount of attention in the past years. As the field grows, it becomes crucial to systematically evaluate the performance of novel computa...

Drug sensitivity prediction from cell line-based pharmacogenomics data: guidelines for developing machine learning models.

Briefings in bioinformatics
The goal of precision oncology is to tailor treatment for patients individually using the genomic profile of their tumors. Pharmacogenomics datasets such as cancer cell lines are among the most valuable resources for drug sensitivity prediction, a cr...

Artificial intelligence and machine learning methods in predicting anti-cancer drug combination effects.

Briefings in bioinformatics
Drug combinations have exhibited promising therapeutic effects in treating cancer patients with less toxicity and adverse side effects. However, it is infeasible to experimentally screen the enormous search space of all possible drug combinations. Th...

iDeepSubMito: identification of protein submitochondrial localization with deep learning.

Briefings in bioinformatics
Mitochondria are membrane-bound organelles containing over 1000 different proteins involved in mitochondrial function, gene expression and metabolic processes. Accurate localization of those proteins in the mitochondrial compartments is critical to t...

Deep learning methods for biomedical named entity recognition: a survey and qualitative comparison.

Briefings in bioinformatics
The biomedical literature is growing rapidly, and the extraction of meaningful information from the large amount of literature is increasingly important. Biomedical named entity (BioNE) identification is one of the critical and fundamental tasks in b...

Increasing the accuracy of single sequence prediction methods using a deep semi-supervised learning framework.

Bioinformatics (Oxford, England)
MOTIVATION: Over the past 50 years, our ability to model protein sequences with evolutionary information has progressed in leaps and bounds. However, even with the latest deep learning methods, the modelling of a critically important class of protein...