Journal of chemical information and modeling
Dec 10, 2025
Promoter sequences across species exhibit both specificity and conservation. The specificity of promoter sequences typically leads to lower cross-species prediction performance compared to within-species prediction. However, conserved promoter motifs...
Traditional fish classification systems suffer from limited training data and imbalanced datasets, particularly for rare or morphologically complex species. This paper presents a novel Generative Adversarial Network architecture that integrates adapt...
Ubiquitination is critical in biomedical research. Predicting ubiquitination sites based on deep learning model have advanced the study of ubiquitination. However, traditional supervised model limits in the scenarios where labels are scarcity across ...
The large-scale application of the mammalian methylation array has substantially expanded the availability of DNA methylation data in mammalian species. However, this data captures only a small portion of species-tissue combinations. To address this,...
Sandflies are vectors for several tropical diseases such as leishmaniasis, bartonellosis, and sandfly fever. Moreover, sandflies exhibit species-specificity in transmitting particular pathogen species, with females being responsible for disease trans...
Deep learning techniques are increasingly utilized to analyze large-scale single-cell RNA sequencing (scRNA-seq) data, offering valuable insights from complex transcriptome datasets. Geneformer, a pre-trained model using a Transformer Encoder archite...
Butterfly wing patterns exhibit notable differences between the dorsal and ventral surfaces, and morphological analyses of them have provided insights into the ecological and behavioural characteristics of wing patterns. Conventional methods for dors...
A deep comparative analysis of brain functional connectome across species in primates has the potential to yield valuable insights for both scientific and clinical applications. However, the interspecies commonality and differences are inherently ent...
Species delimitation in hard corals remains controversial even after 250+ years of taxonomy. Confusing taxonomy in Scleractinia is not the result of sloppy work: clear boundaries are hard to draw because most diagnostic characters are quantitative an...
Epigenetic modifications, particularly RNA methylation and histone alterations, play a crucial role in heredity, development, and disease. Among these, RNA 5-methylcytosine (m5C) is the most prevalent RNA modification in mammalian cells, essential fo...
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