MOTIVATION: Identifying histone tail modifications using ChIP-seq is commonly used in time-series experiments in development and disease. These assays, however, cover specific time-points leaving intermediate or early stages with missing information....
MOTIVATION: Cell polarity refers to the asymmetric organization of cellular components in various cells. Epithelial cells are the best-known examples of polarized cells, featuring apical and basolateral membrane domains. Mounting evidence suggests th...
Advances in single-cell RNA sequencing (scRNA-seq) have furthered the simultaneous classification of thousands of cells in a single assay based on transcriptome profiling. In most analysis protocols, single-cell type annotation relies on marker genes...
INTRODUCTION: Computed tomography (CT) is an auxiliary modality in the diagnosis of the novel Coronavirus (COVID-19) disease and can guide physicians in the presence of lung involvement. In this study, we aimed to investigate the contribution of deep...
Translational vision science & technology
Dec 1, 2021
PURPOSE: Given the robust effectiveness of inhibiting myopia progression, orthokeratology has gained increasing popularity worldwide. However, identifying the boundary and the center of reshaped corneal area (i.e., treatment zone) is the main challen...
Translational vision science & technology
Dec 1, 2021
PURPOSE: Optic nerve damage is the principal feature of glaucoma and contributes to vision loss in many diseases. In animal models, nerve health has traditionally been assessed by human experts that grade damage qualitatively or manually quantify axo...
In this Letter, a deep-learning-based approach is proposed for estimating the strain field distributions in phase-sensitive optical coherence elastography. The method first uses the simulated wrapped phase maps and corresponding phase-gradient maps t...
BACKGROUND AND AIM: Eyelid position and contour abnormality could lead to various diseases, such as blepharoptosis, which is a common eyelid disease. Accurate assessment of eyelid morphology is important in the management of blepharoptosis. We aimed ...
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