AIMC Topic: DNA Repair

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The Effect of Leonurus sibiricus Plant Extracts on Stimulating Repair and Protective Activity against Oxidative DNA Damage in CHO Cells and Content of Phenolic Compounds.

Oxidative medicine and cellular longevity Dec 14, 2015
Leonurus sibiricus L. has been used as a traditional and medicinal herb for many years in Asia and Europe. This species is known to have antibacterial, anti-inflammatory, and antioxidant activity and has demonstrated a reduction of intracellular reac...
Animals Antioxidants Plant Extracts Wound Healing Cell Survival Protective Agents Phenols CHO Cells Cricetulus Oxidation-Reduction DNA Damage Chromatography, High Pressure Liquid Regeneration Spectrometry, Mass, Electrospray Ionization Gene Expression Regulation Cytoprotection Cricetinae DNA Breaks, Double-Stranded DNA Repair Leonurus
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Identification of DNA damage repair-related genes in sepsis using bioinformatics and machine learning: An observational study.

Medicine Jan 31, 2025
Sepsis is a life-threatening disease with a high mortality rate, for which the pathogenetic mechanism still unclear. DNA damage repair (DDR) is essential for maintaining genome integrity. This study aimed to explore the role of DDR-related genes in t...
Humans Machine Learning Biomarkers Sepsis ROC Curve Computational Biology Nomograms DNA Damage Cell Cycle Proteins DNA Repair
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