AIMC Topic: Regeneration
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Unsupervised learning reveals rapid gait adaptation after leg loss and regrowth in spiders.
The Journal of experimental biology
Jun 17, 2025
Many invertebrates voluntarily lose (autotomize) limbs during antagonistic encounters, and some regenerate functional replacements. Because limb loss can have severe consequences on individual fitness, it is likely subject to significant selective pr...
iPSC-RPE patch restores photoreceptors and regenerates choriocapillaris in a pig retinal degeneration model.
JCI insight
May 22, 2025
Dry age-related macular degeneration (AMD) is a leading cause of untreatable vision loss. In advanced cases, retinal pigment epithelium (RPE) cell loss occurs alongside photoreceptor and choriocapillaris degeneration. We hypothesized that an RPE-patc...
Ultrasound-activated piezoelectric biomaterials for cartilage regeneration.
Ultrasonics sonochemistry
Apr 14, 2025
Due to the low density of chondrocytes and limited ability to repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials to support facial structure, restore fu...
Predicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory.
Journal of materials chemistry. B
Mar 5, 2025
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers ...
Application of machine learning in in vitro propagation of endemic Lilium akkusianum R. Gämperle.
PloS one
Jul 25, 2024
A successful regeneration protocol was developed for micropropagation of Lilium akkusianum R. Gämperle, an endemic species of Türkiye, from scale explants. The study also aimed to evaluate the effects of Meta-Topolin (mT) and N6-Benzyladenine (BA) on...
Public sentiment analysis on urban regeneration: A massive data study based on sentiment knowledge enhanced pre-training and latent Dirichlet allocation.
PloS one
Apr 27, 2023
BACKGROUND: Public satisfaction is the ultimate goal and an important determinant of China's urban regeneration plan. This study is the first to use massive data to perform sentiment analysis of public comments on China's urban regeneration.
Anti-inflammatory therapy enables robot-actuated regeneration of aged muscle.
Science robotics
Mar 22, 2023
Robot-actuated mechanical loading (ML)-based therapies ("mechanotherapies") can promote regeneration after severe skeletal muscle injury, but the effectiveness of such approaches during aging is unknown and may be influenced by age-associated decline...
Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles.
Nature aging
Dec 6, 2021
Heterochronic blood exchange (HBE) has demonstrated that circulating factors restore youthful features to aged tissues. However, the systemic mediators of those rejuvenating effects remain poorly defined. We show here that the beneficial effect of yo...
Skeletal muscle regeneration with robotic actuation-mediated clearance of neutrophils.
Science translational medicine
Oct 6, 2021
Mechanical stimulation (mechanotherapy) can promote skeletal muscle repair, but a lack of reproducible protocols and mechanistic understanding of the relation between mechanical cues and tissue regeneration limit progress in this field. To address th...
Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization.
Osteoarthritis and cartilage
Jan 8, 2021
OBJECTIVE: To automate the grading of histological images of engineered cartilage tissues using deep learning.
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