AIMC Topic: Drug Delivery Systems

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Improved drug response prediction by drug target data integration via network-based profiling.

Briefings in bioinformatics
Drug response prediction (DRP) is important for precision medicine to predict how a patient would react to a drug before administration. Existing studies take the cell line transcriptome data, and the chemical structure of drugs as input and predict ...

Review on the Artificial Intelligence-based Nanorobotics Targeted Drug Delivery System for Brain-specific Targeting.

Current pharmaceutical design
Contemporary medical research increasingly focuses on the blood-brain barrier (BBB) to maintain homeostasis in healthy individuals and provide solutions for neurological disorders, including brain cancer. Specialized in vitro modules replicate the BB...

3D Printable Drug Delivery Systems: Next-generation Healthcare Technology and Regulatory Aspects.

Current pharmaceutical design
A revolutionary shift in healthcare has been sparked by the development of 3D printing, propelling us into an era replete with boundless opportunities for personalized DDS (Drug Delivery Systems). Precise control of the kinetics of drug release can b...

Enhancing Therapeutic Delivery Using Micro- and Nanorobots.

IEEE pulse
"The traditional way of delivering drugs has a very low efficiency. For instance, with solid tumors, drug delivery efficiency is reported to be lower than 1% [1], which means that 99% of the drug is elsewhere in the body causing side effects instead ...

Artificial Intelligence in Drug Formulation and Development: Applications and Future Prospects.

Current drug metabolism
Artificial Intelligence (AI) has emerged as a powerful tool in various domains, and the field of drug formulation and development is no exception. This review article aims to provide an overview of the applications of AI in drug formulation and devel...

Application of in Silico Technologies for Drug Target Discovery and Pharmacokinetic Analysis.

Chemical & pharmaceutical bulletin
Drug discovery is researched and developed through many processes, but its overall success rate is extremely low, requiring a very long period of development and considerable costs. Clearly, there is a need to reduce research and development costs by...

Artificial Intelligence Assisted Fabrication of 3D, 4D and 5D Printed Formulations or Devices for Drug Delivery.

Current drug delivery
5D & 4D printings are an advanced version of 3D printing class and are one of the most revolutionary and powerful fabrication methods used for preparing innovative structures and solid substances using precise additive manufacturing technology. It ca...

Towards Micropump- and Microneedle-based Drug Delivery using Micro Transdermal Interface Platforms (MicroTIPs).

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Micro Transdermal Interface Platforms (MicroTIPs) will combine minimally invasive microneedle arrays with highly miniaturized sensors, actuators, control electronics, wireless communications and artificial intelligence. These patch-like devices will ...

Molecular Modeling Techniques Applied to the Design of Multitarget Drugs: Methods and Applications.

Current topics in medicinal chemistry
Multifactorial diseases, such as cancer and diabetes present a challenge for the traditional "one-target, one disease" paradigm due to their complex pathogenic mechanisms. Although a combination of drugs can be used, a multitarget drug may be a bette...

Active disease-related compound identification based on capsule network.

Briefings in bioinformatics
Pneumonia, especially corona virus disease 2019 (COVID-19), can lead to serious acute lung injury, acute respiratory distress syndrome, multiple organ failure and even death. Thus it is an urgent task for developing high-efficiency, low-toxicity and ...