AIMC Topic: Drug Resistance, Microbial

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Antimicrobial use and resistance.

BMJ (Clinical research ed.)
Antimicrobial resistance affects the delivery of safe and effective healthcare. Antimicrobial resistance has attracted strong political focus, with the 2024 United Nations General Assembly high level meeting providing a clear commitment to reducing m...

Global wastewater microbiome reveals core bacterial community and viral diversity with regional antibiotic resistance patterns.

mSystems
Municipal wastewater treatment plants (WWTPs) serve as global repositories for diverse and dynamic microbial communities, reflecting the complex interplay of human activities, environmental conditions, and public health challenges. Despite their impo...

Cross-sectoral synergy governance programme for antimicrobial resistance control in China using a 'One Health' approach: study protocol for a mixed-methods study.

BMJ open
INTRODUCTION: Antimicrobial resistance (AMR) is a critical global public health concern, particularly acute in rural China. Counties, which cover extensive rural regions, face major challenges in AMR governance and thus require priority attention. Ye...

High pollution and health risk of antibiotic resistance genes in rural domestic sewage in southeastern China: A study combining national-scale distribution and machine learning.

Environmental pollution (Barking, Essex : 1987)
Rural domestic sewage has emerged as an important reservoir of antibiotic resistance genes (ARGs) under rapid urbanization, while the national-scale geographical patterns and risks of ARGs remaining unclear. We investigated ARG pollution in rural dom...

Influence of microplastics on antibiotic resistance genes across diverse environments: A comprehensive meta and machine-learning analysis.

Journal of hazardous materials
The coexistence of microplastics (MPs) and antibiotic resistance genes (ARGs) in various environments presents significant ecological risks. However, the influence of MPs properties and environmental conditions shaping ARG dynamics remain unclear. Th...

Machine learning approaches for predicting antibiotic resistance genes abundance changes during biological nitrogen removal process.

Journal of environmental management
Wastewater treatment plants (WWTPs) serve as reservoirs for multiple antimicrobial agents (AAs), thereby promoting the risk of antibiotic resistance genes (ARGs) transmission in sewage and sludge during biological nitrogen removal (BNR) processes. An...

Similar Prophage Induction but Divergent Antibiotic Resistance Gene Occurrence: Leachates and Free Radicals Drive Differential Activation Mechanisms in Aged Tire Crumb Rubber.

Environmental science & technology
Indigenous phages play a key role in the spread of extracellular antibiotic resistance genes (eARGs), and micro/nanocontaminants can exacerbate this process. However, the specific roles and mechanisms of phage communities in this process are still no...

Synergistic effect of horizontal transfer of antibiotic resistance genes between bacteria exposed to microplastics and per/polyfluoroalkyl substances: An explanation from theoretical methods.

Journal of hazardous materials
Microplastics (MPs) and per/polyfluoroalkyl substances (PFASs), as emerging pollutants widely present in aquatic environments, pose a significant threat to human health through the horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs)....

A framework predicting removal efficacy of antibiotic resistance genes during disinfection processes with machine learning.

Journal of hazardous materials
Disinfection has been applied widely for the removal of antibiotic resistance genes (ARGs) to curb the spread of antibiotic resistance. Quantitative polymerase chain reaction (qPCR) is the most used method to quantify the damage of DNA thus calculati...

Preliminary exploration of ChatGPT-4 shows the potential of generative artificial intelligence for culturally tailored, multilingual antimicrobial resistance awareness messaging.

American journal of veterinary research
OBJECTIVE: Antimicrobial resistance (AMR), a global threat driven by factors such as improper antimicrobial use in humans and animals, is projected to cause 10 million annual deaths by 2050. For behavior change, public health messages must be tailore...