AIMC Topic: Dyspepsia

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Exploration of the mechanism of traditional Chinese medicine by AI approach using unsupervised machine learning for cellular functional similarity of compounds in heterogeneous networks, XiaoErFuPi granules as an example.

Pharmacological research Jul 17, 2020
'Polypharmacology' is usually used to describe the network-wide effect of a single compound, but traditional Chinese medicine (TCM) has a polypharmacological effect naturally based on the 'multi-components, multi-targets and multi-pathways' principle...
Humans Animals Male Gene Expression Profiling Transcriptome Protein Interaction Maps Gene Regulatory Networks Systems Biology Duodenum Proteomics Proteome Signal Transduction Medicine, Chinese Traditional Rats, Sprague-Dawley Cluster Analysis Unsupervised Machine Learning Structure-Activity Relationship Molecular Structure Drugs, Chinese Herbal Polypharmacology Dyspepsia
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Innovations in the diagnosis, treatment, and management of disorders of gut-brain interaction (DGBI).

Expert review of gastroenterology & hepatology Jun 1, 2025
INTRODUCTION: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are the most prevalent disorders of gut-brain interaction (DGBI), frequently overlapping and associated with complex pathophysiological mechanisms. Increasing evidence implica...
Humans Gastrointestinal Microbiome Fecal Microbiota Transplantation Probiotics Prebiotics Irritable Bowel Syndrome Dyspepsia Brain-Gut Axis
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