AIMC Topic: Fecal Microbiota Transplantation
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Gut microbiota and SCFAs improve the treatment efficacy of chemotherapy and immunotherapy in NSCLC.
NPJ biofilms and microbiomes
Jul 28, 2025
The role of gut dysbiosis in shaping immunotherapy responses is well-recognized, yet its effect on the therapeutic efficacy of chemotherapy and immunotherapy combinations remains poorly understood. We analyzed gut microbiota in non-small cell lung ca...
Gut microbiome research: Revealing the pathological mechanisms and treatment strategies of type 2 diabetes.
Diabetes, obesity & metabolism
Apr 15, 2025
The high prevalence and disability rate of type 2 diabetes (T2D) caused a huge social burden to the world. Currently, new mechanisms and therapeutic approaches that may affect this disease are being sought. With in-depth research on the pathogenesis ...
Intestinal Microbiome Modulation of Therapeutic Efficacy of Cancer Immunotherapy.
Gastroenterology clinics of North America
Jan 24, 2025
Bacteria are associated with certain cancers and may induce genetic instability and cancer progression. The gut microbiome modulates the response to cancer therapy. Training machine learning models with response associated taxa or bacterial genes pre...
Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review.
Frontiers in immunology
Jan 7, 2025
Immunotherapy, especially immune checkpoint inhibitor (ICI) therapy, has yielded remarkable outcomes for some patients with solid cancers, but others do not respond to these treatments. Recent research has identified the gut microbiota as a key modul...
Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).
PloS one
Dec 27, 2024
BACKGROUND: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diar...
[Association between gut microbiota and hyperuricemia: insights into innovative therapeutic strategies].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Jun 25, 2025
Uric acid (UA) is the final metabolite of purines in the human body. An imbalance in UA production and excretion that disrupts homeostasis leads to elevated blood UA levels and the development of hyperuricemia (HUA). Approximately one-third of UA is ...
Innovations in the diagnosis, treatment, and management of disorders of gut-brain interaction (DGBI).
Expert review of gastroenterology & hepatology
Jun 1, 2025
INTRODUCTION: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are the most prevalent disorders of gut-brain interaction (DGBI), frequently overlapping and associated with complex pathophysiological mechanisms. Increasing evidence implica...
Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling.
Frontiers in immunology
Jan 1, 2025
The important function of microbiota as therapeutic modulators and diagnostic biomarkers in cancer has been shown by recent developments in microbiome research. The intricate interplay between the gut microbiota and the development of cancer, especia...
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