AIMC Topic: Fecal Microbiota Transplantation

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Intestinal Microbiome Modulation of Therapeutic Efficacy of Cancer Immunotherapy.

Gastroenterology clinics of North America Jan 24, 2025
Bacteria are associated with certain cancers and may induce genetic instability and cancer progression. The gut microbiome modulates the response to cancer therapy. Training machine learning models with response associated taxa or bacterial genes pre...
Gastrointestinal Microbiome Immunotherapy Fecal Microbiota Transplantation Humans Neoplasms Immune Checkpoint Inhibitors
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Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review.

Frontiers in immunology Jan 7, 2025
Immunotherapy, especially immune checkpoint inhibitor (ICI) therapy, has yielded remarkable outcomes for some patients with solid cancers, but others do not respond to these treatments. Recent research has identified the gut microbiota as a key modul...
Treatment Outcome Animals Anti-Bacterial Agents Immune Checkpoint Inhibitors Gastrointestinal Microbiome Fecal Microbiota Transplantation Neoplasms Immunotherapy Humans Precision Medicine
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Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).

PloS one Dec 27, 2024
BACKGROUND: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diar...
Anti-Bacterial Agents Prospective Studies Feces Humans Diarrhea Fecal Microbiota Transplantation Female Gastrointestinal Microbiome Clinical Trials, Phase II as Topic Critical Illness Multicenter Studies as Topic Randomized Controlled Trials as Topic Male Dysbiosis
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[Association between gut microbiota and hyperuricemia: insights into innovative therapeutic strategies].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology Jun 25, 2025
Uric acid (UA) is the final metabolite of purines in the human body. An imbalance in UA production and excretion that disrupts homeostasis leads to elevated blood UA levels and the development of hyperuricemia (HUA). Approximately one-third of UA is ...
Fecal Microbiota Transplantation Medicine, Chinese Traditional Gastrointestinal Microbiome Humans Uric Acid Hyperuricemia Prebiotics Probiotics
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Innovations in the diagnosis, treatment, and management of disorders of gut-brain interaction (DGBI).

Expert review of gastroenterology & hepatology Jun 1, 2025
INTRODUCTION: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are the most prevalent disorders of gut-brain interaction (DGBI), frequently overlapping and associated with complex pathophysiological mechanisms. Increasing evidence implica...
Fecal Microbiota Transplantation Probiotics Gastrointestinal Microbiome Dyspepsia Brain-Gut Axis Irritable Bowel Syndrome Prebiotics Humans
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Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling.

Frontiers in immunology Jan 1, 2025
The important function of microbiota as therapeutic modulators and diagnostic biomarkers in cancer has been shown by recent developments in microbiome research. The intricate interplay between the gut microbiota and the development of cancer, especia...
Fecal Microbiota Transplantation Early Detection of Cancer Neoplasms Gastrointestinal Microbiome Animals Humans Biomarkers, Tumor Precision Medicine
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