OBJECTIVE: To develop a random forest model (RFM) to predict implantation potential of a transferred embryo and compare it with a multivariate logistic regression model (MvLRM), based on data from a large cohort including in vitro fertilization (IVF)...
STUDY QUESTION: What is the inter-observer agreement among embryologists for decision to freeze blastocysts of borderline morphology and can it be improved with a modified grading system?
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
33018428
The Uterine Junctional Zone (JZ) is identified as an important anatomical region in the implantation process during assisted reproduction. The JZ changes throughout the hormone stimulation cycle and has predictive value for implantation success. Desp...
RESEARCH QUESTION: Can a deep machine learning artificial intelligence algorithm predict ploidy and implantation in a known data set of static blastocyst images, and how does its performance compare against chance and experienced embryologists?
Embryo evaluation and selection embody the aggregate manifestation of the entire in vitro fertilization (IVF) process. It aims to choose the "best" embryos from the larger cohort of fertilized oocytes, the majority of which will be determined to be n...
Computer methods and programs in biomedicine
33524814
BACKGROUND AND OBJECTIVE: The morphology of the human metaphase II (MII) oocyte is an essential indicator of the embryo's potential for developing into a healthy baby in the Intra-Cytoplasmic Sperm Injection (ICSI) process. In this case, characterist...
Stem cell-based embryo models by cultured pluripotent and extra-embryonic lineage stem cells are novel platforms to model early postimplantation development. We showed that induced pluripotent stem cells (iPSCs) could form ITS (iPSCs and trophectoder...