IEEE journal of biomedical and health informatics
Mar 7, 2022
This study presents a novel approach to automatically perform instant phenotypic assessment of red blood cell (RBC) storage lesion in phase images obtained by digital holographic microscopy. The proposed model combines a generative adversarial networ...
Red blood cells (RBCs) must be highly deformable to transit through the microvasculature to deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural aging, or storage in blood bags can impede the proper function of t...
Macrophages play an important role in the adaptive immune system. Their ability to neutralize cellular targets through Fc receptor-mediated phagocytosis has relied upon immunotherapy that has become of particular interest for the treatment of cancer ...
Holographic cytometry is introduced as an ultra-high throughput implementation of quantitative phase imaging of single cells flowing through parallel microfluidic channels. Here, the approach was applied for characterizing the morphology of individua...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 6, 2021
Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the demand for a...
Malaria is a serious disease responsible for thousands of deaths each year. Many efforts have been made to aid in the diagnosis of malaria using machine learning techniques, but to date, the presence of other elements that may interfere with the reco...
Combining microfluidics technology with machine learning represents an innovative approach to conduct massive quantitative cell behavior study and implement smart decision-making systems in support of clinical diagnostics. The spleen plays a key-role...
Transfusion medicine (Oxford, England)
May 24, 2021
BACKGROUND: The paucity of accurate quantitative standards for determining the quantity of red blood cells (RBCs) needed for perioperative patients and the predominant application of the "preoperative hemoglobin + surgery type" empirical decision-mak...
The investigation of cell shapes mostly relies on the manual classification of 2D images, causing a subjective and time consuming evaluation based on a portion of the cell surface. We present a dual-stage neural network architecture for analyzing fin...
IEEE journal of biomedical and health informatics
May 11, 2021
Computer-assisted algorithms have become a mainstay of biomedical applications to improve accuracy and reproducibility of repetitive tasks like manual segmentation and annotation. We propose a novel pipeline for red blood cell detection and counting ...
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