AIMC Topic: Lab-On-A-Chip Devices
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Diagnostic technologies for neuroblastoma.
Lab on a chip
Jul 23, 2025
Neuroblastoma is an aggressive childhood cancer characterised by high relapse rates and heterogenicity. Current medical diagnostic methods involve an array of techniques, from blood tests to tumour biopsies. This process is associated with long-term ...
AI-CMCA: a deep learning-based segmentation framework for capillary microfluidic chip analysis.
Scientific reports
Jul 21, 2025
Capillary microfluidic chips (CMCs) enable passive liquid transport via surface tension and wettability gradients, making them central to point-of-care diagnostics and biomedical sensing. However, accurate analysis of capillary-driven flow experiment...
Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer.
Journal of translational medicine
Jul 16, 2025
BACKGROUND: Head and neck cancer (HNC) presents significant research challenges due to the complexity of its tumor microenvironment (TME) and the heterogeneity across different cancer subtypes. Recent advancements in three-dimensional (3D) culture mo...
Deep Learning-Enhanced Hand-Driven Spatial Encoding Microfluidics for Multiplexed Molecular Testing at Home.
ACS nano
Jul 8, 2025
The frequent global outbreaks of viral infectious diseases have significantly heightened the urgent demand for molecular testing at home. However, the labor-intensive sample preparation and nucleic acid amplification steps, along with the complexity ...
Advanced droplet microfluidic platform for high-throughput screening of industrial fungi.
Biosensors & bioelectronics
May 16, 2025
Industrial fungi are pivotal candidates for the production of a diverse array of bioproducts. To enhance their productivity, these strains are frequently subjected to genetic modifications. Following transformation, the selection of optimal productio...
Deep learning-assisted 10-μL single droplet-based viscometry for human aqueous humor.
Biosensors & bioelectronics
May 2, 2025
Probing the viscosity of human aqueous humor is crucial for optimizing micro-tube shunts in glaucoma treatment. However, conventional viscometers are not suitable for aqueous humor due to the limited sample volume-only tens of microliters-that can be...
Optimizing microfluidic chip for rapid SARS-CoV-2 detection using Taguchi method and artificial neural network PSO.
Scientific reports
Apr 23, 2025
Microfluidic biosensors offer a promising solution for real-time analysis of coronaviruses with minimal sample volumes. This study optimizes a biochip for the rapid detection of SARS-CoV-2 using the Taguchi orthogonal table L(3), which comprises nine...
Artificial intelligence in preclinical research: enhancing digital twins and organ-on-chip to reduce animal testing.
Drug discovery today
Apr 17, 2025
Artificial intelligence (AI) is reshaping preclinical drug research offering innovative alternatives to traditional animal testing. Advanced techniques, including machine learning (ML), deep learning (DL), AI-powered digital twins (DTs), and AI-enhan...
Deep-Learning-Assisted Microfluidic Immunoassay via Smartphone-Based Imaging Transcoding System for On-Site and Multiplexed Biosensing.
Nano letters
Apr 9, 2025
Point-of-care testing (POCT) with multiplexed capability, ultrahigh sensitivity, affordable smart devices, and user-friendly operation is critically needed for clinical diagnostics and food safety. This study presents a deep-learning-assisted microfl...
Deep Learning-driven Microfluidic-SERS to Characterize the Heterogeneity in Exosomes for Classifying Non-Small Cell Lung Cancer Subtypes.
ACS sensors
Apr 1, 2025
Lung cancer exhibits strong heterogeneity, and its early diagnosis and precise subtyping are of great importance, as they can increase the ability to deliver personalized medicines by tailoring therapy regimens. Tissue biopsy, albeit the gold standar...
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