The BBB remains a major obstacle to effective treatment of CNS disorders by limiting the entry of most therapeutics into the brain. The hCMEC/D3 is widely used as anin vitromodel to study BBB structure, permeability, and drug transport. In parallel, ...
BACKGROUND: Cancer is the second leading cause of death worldwide. While significant progress has been made in early detection and treatment, metastasis remains the major cause of cancer-related morbidity and mortality. In the last decade the rate of...
At-home testing facilitates early screening and longitudinal monitoring of immune disorders, significantly enhancing patient engagement in personalized healthcare management. This convenient self-testing capability primarily stems from advancements i...
Urinary glucose, creatinine, and uric acid are vital biomarkers for diabetes and kidney disease management. However, multiplex point-of-care detection faces challenges due to insufficient sensitivity in complex urine matrices and signal cross-talk fr...
Single-cell analysis has advanced biomedical research by revealing cellular heterogeneity with unprecedented resolution, identifying rare subpopulations that drive disease progression and therapeutic resistance. Microfluidics is central to this advan...
The escalating global threat of antimicrobial resistance (AMR) necessitates a paradigm shift towards rapid and scalable diagnostic technologies. Conventional antimicrobial susceptibility testing (AST) methods, while reliable, are hindered by prolonge...
Single-cell analysis is essential for uncovering heterogeneous biological functions that arise from intricate cellular responses. Here, microfluidic droplet arrays enable high-throughput data collection through cell encapsulation in picoliter volumes...
Male infertility affects a significant portion of couples worldwide, with standard semen analysis often failing to identify functional deficiencies in sperm performance. This study presents a microfluidic platform for characterizing sperm flagellar b...
Recently, the integration of smartphone-based platforms into biomedical sensing has provided portable, low-cost, and scalable alternatives to conventional laboratory diagnostics. According to the advances in mobile imaging, embedded sensors, microflu...
Journal of controlled release : official journal of the Controlled Release Society
Nov 1, 2025
Lipid nanoparticles have emerged as valuable gene delivery systems paving the way for next-generation vaccine and cancer therapeutics. Inevitably, this evolution is carried by dissecting and rationalizing the vehicles' complex formulation process. Gi...
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