AIMC Topic: Fos-Related Antigen-2

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Multi-level validation of high expression of PLAUR, FOSL2, and SLC11A1 in aortic dissection and their clinical implications.

International immunopharmacology Sep 2, 2025
Macrophages, pivotal orchestrators of the immune system, are integral to the initiation of specific immune responses and exert profound influence on the pathogenesis, progression, and therapeutic landscape of aortic dissection (AD). Leveraging the pr...
Humans Macrophages Female Animals Male Middle Aged Single-Cell Analysis Mice Mice, Inbred C57BL Aortic Dissection Cation Transport Proteins Fos-Related Antigen-2
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Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium.

The Journal of international medical research Apr 27, 2025
BackgroundKnee osteoarthritis is a debilitating disease with a complex pathogenesis. Synovitis, which refers to inflammation of the synovial membrane surrounding the joint, is believed to play an important role in the development and progression of k...
Humans Machine Learning Animals Gene Expression Profiling Gene Regulatory Networks Mice Synovial Membrane Disease Models, Animal Gene Expression Regulation Osteoarthritis, Knee Fos-Related Antigen-2
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