AIMC Topic: Aortic Dissection

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Development and validation of a predictive model for postoperative acute respiratory distress syndrome in patients with type A aortic dissection based on the 2023 updated definition.

Respiratory research
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a common complication after type A aortic dissection surgery and often leads to worsened clinical outcomes for patients. The early prediction of postoperative ARDS is a crucial challenge in cl...

Genome wide DNA methylation and transcriptome integration analysis reveals potential markers in type A aortic dissection pathogenesis.

Scientific reports
Type A aortic dissection (TAAD) is a vascular disease with high mortality; however, the role of gene methylation in its pathogenesis has received little attention. This study aimed to identify candidate markers of TAAD by integrating methylation and ...

Automated AI detection of thoracic aortic dissection on CT imaging.

European radiology experimental
BACKGROUND: Aortic dissection (AD) is a life-threatening condition. We developed an artificial intelligence (AI) algorithm capable of robust, accurate, and automated AD detection and sub-classification.

Multi-level validation of high expression of PLAUR, FOSL2, and SLC11A1 in aortic dissection and their clinical implications.

International immunopharmacology
Macrophages, pivotal orchestrators of the immune system, are integral to the initiation of specific immune responses and exert profound influence on the pathogenesis, progression, and therapeutic landscape of aortic dissection (AD). Leveraging the pr...

Lactylation associated biomarkers and immune infiltration in aortic dissection.

Scientific reports
Protein lactylation, a novel post-translational modification (PTM), has emerged as a critical factor in disease processes related to glycolysis and immune responses. However, its role in aortic dissection (AD) has yet to be thoroughly investigated. T...

Preoperative prediction of major adverse outcomes after total arch replacement in acute type A aortic dissection based on machine learning ensemble.

Scientific reports
A machine learning model was developed and validated to predict postoperative complications in patients with acute type A aortic dissection (ATAAD) who underwent total arch replacement combined with frozen elephant trunk (TAR + FET), with the goal of...

A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.

Scientific reports
This study aimed to demonstrate whether plasma galectin-3 could predict the development of postoperative delirium (POD) in patients with acute aortic dissection (AAD). Prospective, observational study. Cardiac surgery intensive care unit. Consecutive...

Investigating long-term risk of aortic aneurysm and dissection from fluoroquinolones and the key contributing factors using machine learning methods.

Scientific reports
The connection between fluoroquinolones and severe heart conditions, such as aortic aneurysm (AA) and aortic dissection (AD), has been acknowledged, but the full extent of long-term risks remains uncertain. Addressing this knowledge deficit, a retros...

Interpretable prognostic modeling for long-term survival of Type A aortic dissection patients using support vector machine algorithm.

European journal of medical research
OBJECTIVES: This study aims to develop a reliable and interpretable predictive model for long-term survival in Type A aortic dissection (TAAD) patients, utilizing machine learning (ML) algorithms.