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Gene Rearrangement

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Direct identification of ALK and ROS1 fusions in non-small cell lung cancer from hematoxylin and eosin-stained slides using deep learning algorithms.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 36057739
Anaplastic lymphoma kinase (ALK) and ROS oncogene 1 (ROS1) gene fusions are well-established key players in non-small cell lung cancer (NSCLC). Although their frequency is relatively low, their detection is important for patient care and guides thera...
Anaplastic Lymphoma Kinase Carcinoma, Non-Small-Cell Lung Deep Learning Eosine Yellowish-(YS) Gene Rearrangement Hematoxylin Humans In Situ Hybridization, Fluorescence Lung Neoplasms Oncogene Proteins, Fusion Protein-Tyrosine Kinases Proto-Oncogene Proteins
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MYC Rearrangement Prediction From LYSA Whole Slide Images in Large B-Cell Lymphoma: A Multicentric Validation of Self-supervised Deep Learning Models.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 39265953
Large B-cell lymphoma (LBCL) is a heterogeneous lymphoid malignancy in which MYC gene rearrangement (MYC-R) is associated with a poor prognosis, prompting the recommendation for more intensive treatment. MYC-R detection relies on fluorescence in situ...
Aged Deep Learning Female Gene Rearrangement Humans Image Interpretation, Computer-Assisted In Situ Hybridization, Fluorescence Lymphoma, Large B-Cell, Diffuse Male Middle Aged Proto-Oncogene Proteins c-myc Reproducibility of Results
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