AIMC Topic: Genome, Viral
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Influenza virus genotype to phenotype predictions through machine learning: a systematic review.
Emerging microbes & infections
Dec 1, 2021
BACKGROUND: There is great interest in understanding the viral genomic predictors of phenotypic traits that allow influenza A viruses to adapt to or become more virulent in different hosts. Machine learning techniques have demonstrated promise in add...
VIDHOP, viral host prediction with deep learning.
Bioinformatics (Oxford, England)
Apr 20, 2021
MOTIVATION: Zoonosis, the natural transmission of infections from animals to humans, is a far-reaching global problem. The recent outbreaks of Zikavirus, Ebolavirus and Coronavirus are examples of viral zoonosis, which occur more frequently due to gl...
Victors: a web-based knowledge base of virulence factors in human and animal pathogens.
Nucleic acids research
Jan 8, 2019
Virulence factors (VFs) are molecules that allow microbial pathogens to overcome host defense mechanisms and cause disease in a host. It is critical to study VFs for better understanding microbial pathogenesis and host defense mechanisms. Victors (ht...
Phylogenomics and Infectious Potential of Avian Avulaviruses Species-Type 1 Isolated from Healthy Green-Winged Teal () from a Wetland Sanctuary of Indus River.
Avian diseases
Dec 1, 2018
Given the importance of (AAvVs) in commercial poultry, continuous monitoring and surveillance in natural reservoirs (waterfowls) is imperative. Here, we report full genomic and biologic characterization of two virulent AAvVs isolated from apparently...
Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes.
Science (New York, N.Y.)
Nov 2, 2018
Identifying the animal origins of RNA viruses requires years of field and laboratory studies that stall responses to emerging infectious diseases. Using large genomic and ecological datasets, we demonstrate that animal reservoirs and the existence an...
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