AIMC Topic: Larva

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Artificial intelligence (AI)-driven morphological assessment of zebrafish larvae for developmental toxicity chemical screening.

Aquatic toxicology (Amsterdam, Netherlands)
Screening chemicals using the zebrafish embryo developmental toxicity assay requires visual assessment of larval morphological changes based on images by experienced screeners. The process is time-consuming and prone to subjectivity. However, deep le...

Machine learning-based text mining for cutaneous myiasis and potential value of an accidental maggot therapy for complicated skin and soft tissue infection with sepsis.

Frontiers in cellular and infection microbiology
BACKGROUND: Cutaneous myiasis, one of the most frequently diagnosed myiasis types, is defined as skin or soft tissue on a living host infested by dipterous larvae (maggots). However, bibliometric analysis of this disease remains sparse. Machine learn...

Microbiome determinants of productivity in aquaculture of whiteleg shrimp.

Applied and environmental microbiology
UNLABELLED: Aquaculture holds immense promise for addressing the food needs of our growing global population. Yet, a quantitative understanding of the factors that control its efficiency and productivity has remained elusive. In this study, we addres...

Intelligent larval zebrafish phenotype recognition via attention mechanism for high-throughput screening.

Computers in biology and medicine
BACKGROUND: Larval zebrafish phenotypes serve as critical research indicators in fields such as ecotoxicology and safety assessment since phenotypic defects are closely related to alterations of underlying pathway. However, identifying these defects ...

A machine-learning approach to optimize nutritional properties and organic wastes recycling efficiency conversed by black soldier fly (Hermetia illucens).

Bioresource technology
Suboptimal nutrition in organic waste limits the growth of black soldier fly (BSF) larvae, thereby reducing biowaste recycling efficiency. In this study, weight gain data from BSF larvae fed diets with distinct nutrient compositions were used to buil...

Deep learning-driven behavioral analysis reveals adaptive responses in Drosophila offspring after long-term parental microplastic exposure.

Journal of environmental management
Microplastics are widely distributed in the environment and pose potential hazards to organisms. However, our understanding of the transgenerational effects of microplastics on terrestrial organisms remains limited. In this study, we focused on the m...

Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Scientific reports
Hundreds of loci have been robustly associated with obesity-related traits, but functional characterization of candidate genes remains a bottleneck. Aiming to systematically characterize candidate genes for a role in accumulation of lipids in adipocy...

Machine learning enables high-throughput, low-replicate screening for novel anti-seizure targets and compounds using combined movement and calcium fluorescence in larval zebrafish.

European journal of pharmacology
Identifying new anti-seizure medications (ASMs) is difficult due to limitations in animal-based assays. Zebrafish (Danio rerio) serve as a model for chemical and genetic seizures, but current methods for detecting anti-seizure responses are limited b...

Marigold: a machine learning-based web app for zebrafish pose tracking.

BMC bioinformatics
BACKGROUND: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they ...

The Effect of Different Bleaching Techniques Using 6% Hydrogen Peroxide: Penetration Inside the Pulp Cavity, Bleaching Efficacy and Toxicity.

Brazilian dental journal
This in vitro study aimed to quantify the penetration of hydrogen peroxide (HP), bleaching efficacy (BE) and toxicity in larvae in different bleaching techniques using 6% HP. Sixty maxillary premolars were divided in six groups (n = 10): Pola Luminat...