AIMC Topic: HEK293 Cells

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Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.

Molecular bioSystems Jul 25, 2017
Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, e...
Humans Machine Learning Colon Drug Discovery Antineoplastic Agents Cell Line, Tumor Epithelial Cells Cell Survival Gene Expression Inhibitory Concentration 50 Enzyme Inhibitors HEK293 Cells Databases, Chemical Organ Specificity Naphthoquinones Flap Endonucleases
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Silica Cross-Linked Micellar Core--Shell Nanoparticles Encapsulating IR-780 with Strong Bright and Good Biocompatibility for Optical Imaging In Vivo.

Journal of biomedical nanotechnology Feb 1, 2017
IR-780 iodide, a near-infrared (NIR) fluorescent heptamethine dye, has attracted wide attention in the biomedical community. However, hydrophobicity and toxicity severely limit its further biomedical application. Although many successful efforts have...
Humans Animals Spectroscopy, Near-Infrared Mice Nanoparticles Mice, Nude Mice, Inbred BALB C Cell Survival Silicon Dioxide Fluorescent Dyes Indoles Micelles HEK293 Cells Sentinel Lymph Node Optical Imaging Neoplasms, Experimental
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[Construction of Recombinant Adenovirus Vector with Human/Mouse Interferon Gene and Its Transfection into Human Umbilical Cord Mesenchymal Stem Cells].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Nov 1, 2015
OBJECTIVE: Construction and identification of recombinant adenovirus vector with human/mouse interferon (IFN-gamma) and effectively transfection into human umbilical cord mesenchymal stem cells (HUMSCs).
Humans Animals Mice Enzyme-Linked Immunosorbent Assay Blotting, Western Microscopy, Fluorescence Mesenchymal Stem Cells Transfection HEK293 Cells Plasmids Polymerase Chain Reaction Umbilical Cord Green Fluorescent Proteins Interferons Adenoviridae Genetic Vectors
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