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High-Temperature Requirement A Serine Peptidase 1

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Assessment of and polymorphisms in age-related macular degeneration using classic and machine-learning approaches.

Ophthalmic genetics
BACKGROUND: and are pivotal genes driving increased risk for age-related macular degeneration (AMD) among several populations. Here, we performed a hospital-based case-control study to evaluate the effects of three single nucleotide polymorphisms (...

Chances and challenges of machine learning-based disease classification in genetic association studies illustrated on age-related macular degeneration.

Genetic epidemiology
Imaging technology and machine learning algorithms for disease classification set the stage for high-throughput phenotyping and promising new avenues for genome-wide association studies (GWAS). Despite emerging algorithms, there has been no successfu...