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Complement Factor H

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Assessment of and polymorphisms in age-related macular degeneration using classic and machine-learning approaches.

Ophthalmic genetics
BACKGROUND: and are pivotal genes driving increased risk for age-related macular degeneration (AMD) among several populations. Here, we performed a hospital-based case-control study to evaluate the effects of three single nucleotide polymorphisms (...

Genetic prediction of ICU hospitalization and mortality in COVID-19 patients using artificial neural networks.

Journal of cellular and molecular medicine
There is an unmet need of models for early prediction of morbidity and mortality of Coronavirus disease-19 (COVID-19). We aimed to a) identify complement-related genetic variants associated with the clinical outcomes of ICU hospitalization and death,...