Multiple sclerosis (Houndmills, Basingstoke, England)
May 13, 2024
Artificial intelligence (AI) is the branch of science aiming at creating algorithms able to carry out tasks that typically require human intelligence. In medicine, there has been a tremendous increase in AI applications thanks to increasingly powerfu...
Journal of chemical information and modeling
May 13, 2024
Personalized cancer treatment requires a thorough understanding of complex interactions between drugs and cancer cell lines in varying genetic and molecular contexts. To address this, high-throughput screening has been used to generate large-scale dr...
Journal of chemical information and modeling
May 13, 2024
Central nervous system (CNS) drugs have had a significant impact on treating a wide range of neurodegenerative and psychiatric disorders. In recent years, deep learning-based generative models have shown great potential for accelerating drug discover...
Journal of chemical information and modeling
May 13, 2024
Today, machine learning methods are widely employed in drug discovery. However, the chronic lack of data continues to hamper their further development, validation, and application. Several modern strategies aim to mitigate the challenges associated w...
ACS applied materials & interfaces
May 13, 2024
Cosmetics and topical medications, such as gels, foams, creams, and lotions, are viscoelastic substances that are applied to the skin or mucous membranes. The human perception of these materials is complex and involves multiple sensory modalities. Tr...
Cell reports methods
May 13, 2024
Predicting cellular responses to perturbations requires interpretable insights into molecular regulatory dynamics to perform reliable cell fate control, despite the confounding non-linearity of the underlying interactions. There is a growing interest...
Sensors (Basel, Switzerland)
May 13, 2024
This work presents a retrospective analysis of indoor CO measurements obtained with a mobile robot in an educational building after the COVID-19 lockdown (May 2021), at a time when public activities resumed with mandatory local pandemic restrictions....
Sensors (Basel, Switzerland)
May 13, 2024
During robot-assisted rehabilitation, failure to recognize lower limb movement may efficiently limit the development of exoskeleton robots, especially for individuals with knee pathology. A major challenge encountered with surface electromyography (s...
Tomography (Ann Arbor, Mich.)
May 13, 2024
Radiation treatment of cancers like prostate or cervix cancer requires considering nearby bone structures like vertebrae. In this work, we present and validate a novel automated method for the 3D segmentation of individual lumbar and thoracic vertebr...
Biomolecules
May 13, 2024
The quality prediction of quaternary structure models of a protein complex, in the absence of its true structure, is known as the Estimation of Model Accuracy (EMA). EMA is useful for ranking predicted protein complex structures and using them approp...