AIMC Topic: Humans

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Interpretability Analysis of One-Year Mortality Prediction for Stroke Patients Based on Deep Neural Network.

IEEE journal of biomedical and health informatics
Clinically, physicians collect the benchmark medical data to establish archives for a stroke patient and then add the follow up data regularly. It has great significance on prognosis prediction for stroke patients. In this paper, we present an interp...

Learning Multi-Scale Heterogeneous Representations and Global Topology for Drug-Target Interaction Prediction.

IEEE journal of biomedical and health informatics
Identification of interactions between drugs and target proteins plays a critical role not only in drug discovery but also in drug repositioning. Deep integration of inter-connections and intra-similarities between heterogeneous multi-source data abo...

FCNGRU: Locating Transcription Factor Binding Sites by Combing Fully Convolutional Neural Network With Gated Recurrent Unit.

IEEE journal of biomedical and health informatics
Deciphering the relationship between transcription factors (TFs) and DNA sequences is very helpful for computational inference of gene regulation and a comprehensive understanding of gene regulation mechanisms. Transcription factor binding sites (TFB...

Deep Learning Based Centerline-Aggregated Aortic Hemodynamics: An Efficient Alternative to Numerical Modeling of Hemodynamics.

IEEE journal of biomedical and health informatics
Image-based patient-specific modelling of hemodynamics are gaining increased popularity as a diagnosis and outcome prediction solution for a variety of cardiovascular diseases. While their potential to improve diagnostic capabilities and thereby clin...

Time-Frequency Analysis of Scalp EEG With Hilbert-Huang Transform and Deep Learning.

IEEE journal of biomedical and health informatics
Electroencephalography (EEG) is a brain imaging approach that has been widely used in neuroscience and clinical settings. The conventional EEG analyses usually require pre-defined frequency bands when characterizing neural oscillations and extracting...

Contrastive Cross-Modal Pre-Training: A General Strategy for Small Sample Medical Imaging.

IEEE journal of biomedical and health informatics
A key challenge in training neural networks for a given medical imaging task is the difficulty of obtaining a sufficient number of manually labeled examples. In contrast, textual imaging reports are often readily available in medical records and cont...

Data Pre-Processing Using Neural Processes for Modeling Personalized Vital-Sign Time-Series Data.

IEEE journal of biomedical and health informatics
Clinical time-series data retrieved from electronic medical records are widely used to build predictive models of adverse events to support resource management. Such data is often sparse and irregularly-sampled, which makes it challenging to use many...

Real-Time Hierarchical Classification of Time Series Data for Locomotion Mode Detection.

IEEE journal of biomedical and health informatics
OBJECTIVE: Accurate real-time estimation of motion intent is critical for rendering useful assistance using wearable robotic prosthetic and exoskeleton devices during user-initiated motions. We aim to evaluate hierarchical classification as a strateg...

A Meta-Learning Approach for Fast Personalization of Modality Translation Models in Wearable Physiological Sensing.

IEEE journal of biomedical and health informatics
Modality translation grants diagnostic value to wearable devices by translating signals collected from low-power sensors to their highly-interpretable counterparts that are more familiar to healthcare providers. For instance, bio-impedance (Bio-Z) is...

Predicting Brain Age Using Machine Learning Algorithms: A Comprehensive Evaluation.

IEEE journal of biomedical and health informatics
Machine learning (ML) algorithms play a vital role in the brain age estimation frameworks. The impact of regression algorithms on prediction accuracy in the brain age estimation frameworks have not been comprehensively evaluated. Here, we sought to a...