Humans

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Classification of ECG heartbeats using nonlinear decomposition methods and support vector machine.

Computers in biology and medicine
Classifying electrocardiogram (ECG) heartbeats for arrhythmic risk prediction is a challenging task due to minute variations in the amplitude, duration and morphology of the ECG signal. In this paper, we propose two feature extraction approaches to c...

Fully automatic detection of lung nodules in CT images using a hybrid feature set.

Medical physics
PURPOSE: The aim of this study was to develop a novel technique for lung nodule detection using an optimized feature set. This feature set has been achieved after rigorous experimentation, which has helped in reducing the false positives significantl...

Machine Learning and Network Analysis of Molecular Dynamics Trajectories Reveal Two Chains of Red/Ox-specific Residue Interactions in Human Protein Disulfide Isomerase.

Scientific reports
The human protein disulfide isomerase (hPDI), is an essential four-domain multifunctional enzyme. As a result of disulfide shuffling in its terminal domains, hPDI exists in two oxidation states with different conformational preferences which are impo...
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Automatic Recognition of fMRI-Derived Functional Networks Using 3-D Convolutional Neural Networks.

IEEE transactions on bio-medical engineering
Current functional magnetic resonance imaging (fMRI) data modeling techniques, such as independent component analysis and sparse coding methods, can effectively reconstruct dozens or hundreds of concurrent interacting functional brain networks simult...

Modeling Task fMRI Data Via Deep Convolutional Autoencoder.

IEEE transactions on medical imaging
Task-based functional magnetic resonance imaging (tfMRI) has been widely used to study functional brain networks under task performance. Modeling tfMRI data is challenging due to at least two problems: the lack of the ground truth of underlying neura...

NewGOA: Predicting New GO Annotations of Proteins by Bi-Random Walks on a Hybrid Graph.

IEEE/ACM transactions on computational biology and bioinformatics
A remaining key challenge of modern biology is annotating the functional roles of proteins. Various computational models have been proposed for this challenge. Most of them assume the annotations of annotated proteins are complete. But in fact, many ...

Data mining and pathway analysis of glucose-6-phosphate dehydrogenase with natural language processing.

Molecular medicine reports
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, ...
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DrugSemantics: A corpus for Named Entity Recognition in Spanish Summaries of Product Characteristics.

Journal of biomedical informatics
For the healthcare sector, it is critical to exploit the vast amount of textual health-related information. Nevertheless, healthcare providers have difficulties to benefit from such quantity of data during pharmacotherapeutic care. The problem is tha...