Classifying electrocardiogram (ECG) heartbeats for arrhythmic risk prediction is a challenging task due to minute variations in the amplitude, duration and morphology of the ECG signal. In this paper, we propose two feature extraction approaches to c...
PURPOSE: The aim of this study was to develop a novel technique for lung nodule detection using an optimized feature set. This feature set has been achieved after rigorous experimentation, which has helped in reducing the false positives significantl...
The human protein disulfide isomerase (hPDI), is an essential four-domain multifunctional enzyme. As a result of disulfide shuffling in its terminal domains, hPDI exists in two oxidation states with different conformational preferences which are impo...
IEEE transactions on bio-medical engineering
Jun 15, 2017
Current functional magnetic resonance imaging (fMRI) data modeling techniques, such as independent component analysis and sparse coding methods, can effectively reconstruct dozens or hundreds of concurrent interacting functional brain networks simult...
Task-based functional magnetic resonance imaging (tfMRI) has been widely used to study functional brain networks under task performance. Modeling tfMRI data is challenging due to at least two problems: the lack of the ground truth of underlying neura...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 15, 2017
A remaining key challenge of modern biology is annotating the functional roles of proteins. Various computational models have been proposed for this challenge. Most of them assume the annotations of annotated proteins are complete. But in fact, many ...
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, ...
For the healthcare sector, it is critical to exploit the vast amount of textual health-related information. Nevertheless, healthcare providers have difficulties to benefit from such quantity of data during pharmacotherapeutic care. The problem is tha...
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