AIMC Topic: Knowledge Bases

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Oncotherapy: A System for Requesting Chemotherapy Protocols.

Studies in health technology and informatics
A clinical decision support system is able to provide oncologists with suitable treatment options at the moment of decision making regarding which chemotherapy protocol is the best to apply to a particular oncological case. The National Cancer Instit...

Fuzzy-Arden-Syntax-based, Vendor-agnostic, Scalable Clinical Decision Support and Monitoring Platform.

Studies in health technology and informatics
This study's objective is to develop and use a scalable genuine technology platform for clinical decision support based on Arden Syntax, which was extended by fuzzy set theory and fuzzy logic. Arden Syntax is a widely recognized formal language for r...

Real-time Data Fusion Platforms: The Need of Multi-dimensional Data-driven Research in Biomedical Informatics.

Studies in health technology and informatics
Systems designed to expedite data preprocessing tasks such as data discovery, interpretation, and integration that are required before data analysis drastically impact the pace of biomedical informatics research. Current commercial interactive and re...

Annotation methods to develop and evaluate an expert system based on natural language processing in electronic medical records.

Studies in health technology and informatics
The objective of the SYNODOS collaborative project was to develop a generic IT solution, combining a medical terminology server, a semantic analyser and a knowledge base. The goal of the project was to generate meaningful epidemiological data for var...

Rule-based Cervical Spine Defect Classification Using Medical Narratives.

Studies in health technology and informatics
Classifying the defects occurring at the cervical spine provides the basis for surgical treatment planning and therapy recommendation. This process requires evidence from patient records. Further, the degree of a defect needs to be encoded in a stand...

Acquiring Plausible Predications from MEDLINE by Clustering MeSH Annotations.

Studies in health technology and informatics
The massive accumulation of biomedical knowledge is reflected by the growth of the literature database MEDLINE with over 23 million bibliographic records. All records are manually indexed by MeSH descriptors, many of them refined by MeSH subheadings....

Conceptual Knowledge Discovery in Databases for Drug Combinations Predictions in Malignant Melanoma.

Studies in health technology and informatics
The worldwide incidence of melanoma is rising faster than any other cancer, and prognosis for patients with metastatic disease is poor. Current targeted therapies are limited in their durability and/or effect size in certain patient populations due t...

Generation of Natural-Language Textual Summaries from Longitudinal Clinical Records.

Studies in health technology and informatics
Physicians are required to interpret, abstract and present in free-text large amounts of clinical data in their daily tasks. This is especially true for chronic-disease domains, but holds also in other clinical domains. We have recently developed a p...

Health Informatics: Developing a Masters Programme in Rwanda based on the IMIA Educational Recommendations and the IMIA Knowledge Base.

Studies in health technology and informatics
Since 2011, the Regional e-Health Center of Excellence in Rwanda (REHCE) has run an MSc in Health Informatics programme (MSc HI). A programme review was commissioned in February 2014 after 2 cohorts of students completed the post-graduate certificate...

An Ontology-Based Clinical Decision Support System for the Management of Patients with Multiple Chronic Disorders.

Studies in health technology and informatics
Decision support systems, as means of disseminating clinical practice guidelines, are powerful software that may lead to an improvement of medical practices. However, they are not always efficient and may suffer from limitations among which are lack ...