Genomics, proteomics & bioinformatics
Jan 11, 2019
As a newly-identified protein post-translational modification, malonylation is involved in a variety of biological functions. Recognizing malonylation sites in substrates represents an initial but crucial step in elucidating the molecular mechanisms ...
IEEE transactions on bio-medical engineering
Jan 10, 2019
Continuous human motion intent learning may be modeled using a Gaussian process (GP) autoregression based evolving system to cope with the unspecified and time-varying motion patterns. Electromyography (EMG) signals are the primary input. GP is used ...
BACKGROUND: Conversion of human somatic cells into induced pluripotent stem cells (iPSCs) is often an inefficient, time consuming and expensive process. Also, the tendency of iPSCs to revert to their original somatic cell type over time continues to ...
BMC medical informatics and decision making
Jan 10, 2019
BACKGROUND: Adverse drug events (ADEs) as well as other preventable adverse events in the hospital setting incur a yearly monetary cost of approximately $3.5 billion, in the United States alone. Therefore, it is of paramount importance to reduce the ...
In this paper, data from two studies relative to the relationship between the electroencephalogram (EEG) activities of two isolated and physically separated subjects were re-analyzed using machine-learning algorithms. The first dataset comprises the...
BACKGROUND: Mesothelioma is a lung cancer that kills thousands of people worldwide annually, especially those with exposure to asbestos. Diagnosis of mesothelioma in patients often requires time-consuming imaging techniques and biopsies. Machine lear...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
We introduce here ML4Tox, a framework offering Deep Learning and Support Vector Machine models to predict agonist, antagonist, and binding activities of chemical compounds, in this case for the estrogen receptor ligand-binding domain. The ML4Tox mode...
IEEE journal of biomedical and health informatics
Jan 9, 2019
The accumulating evidences regarding circular RNAs (circRNAs) indicate that they play crucial roles in a wide range of biological processes and participate in tumorigenesis and progression. The number of newly discovered circRNAs have increased drama...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.