AIMC Topic: Meningococcal Vaccines

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Invasive meningococcal disease in adolescents in Europe and select geographies: Disease burden, unmet medical need, and optimizing prevention.

Human vaccines & immunotherapeutics Oct 23, 2025
Invasive meningococcal disease (IMD) is uncommon but serious; the case fatality rate is 8-15% and up to 20-40% of survivors experience disabling sequelae, with a substantial socioeconomic impact. Although incidence is highest in infants and young chi...
Humans Young Adult Brazil Adolescent Incidence Vaccination Australia Europe New Zealand Meningococcal Vaccines Vaccination Coverage Cost of Illness Immunization Programs Meningococcal Infections Neisseria meningitidis
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Modeling protective meningococcal antibody responses and factors influencing antibody persistence following vaccination with MenAfriVac using machine learning.

PloS one Jan 1, 2025
Meningococcal meningitis poses a significant public health burden in the meningitis belt region of sub-Saharan Africa. The introduction of the meningococcal PsA-TT vaccine (MenAfriVac®) has successfully eliminated Neisseria meningitidis serogroup A (...
Humans Machine Learning Female Young Adult Adult Male Adolescent Child, Preschool Child Vaccination Antibodies, Bacterial Meningococcal Vaccines Antibody Formation Meningitis, Meningococcal
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Safety and Immunogenicity of Two Doses of a Quadrivalent Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Indian and Russian Children Aged 9 to 17 Months.

Indian pediatrics Dec 15, 2018
OBJECTIVE: Evaluation of tolerability, safety and immunogenicity of a two-dose series of a quadrivalent meningococcal polysaccharide diptheria toxoid conjugate (ACYW-D) vaccine in Indian and Russian infants/toddlers.
Humans Patient Safety Female Male Infant India Diphtheria Toxoid Meningococcal Vaccines Russia Vaccines, Conjugate
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