AIMC Topic: Antibodies, Bacterial

Clear Filters Showing 1 to 8 of 8 articles

Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding.

Frontiers in immunology May 16, 2025
INTRODUCTION: Lyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the US and increasing incidence. Differentiating Lyme disease, especially in its early stages, f...
Humans Machine Learning Biomarkers Female Lyme Disease Serologic Tests Antibodies, Bacterial Borrelia burgdorferi Adult Male Middle Aged Diagnosis, Differential
View on PubMed DOI

Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence.

mBio Oct 31, 2023
Vaccines to curb the global spread of multidrug-resistant gonorrhea are urgently needed. Here, 26 vaccine candidates identified by an artificial intelligence-driven platform (Efficacy Discriminative Educated Network[EDEN]) were screened for efficacy ...
Artificial Intelligence Female Neisseria gonorrhoeae Gonorrhea Antibodies, Bacterial Vagina Animals Mice Disease Models, Animal Bacterial Proteins Antigens, Bacterial Cell Division Bacterial Vaccines
View on PubMed DOI

Seroprevalence of antibodies for pertussis and diphtheria among people leaving or entering China: a cross-sectional study.

Journal of infection in developing countries May 31, 2019
INTRODUCTION: Despite high population immunity, pertussis remains one of the leading causes of vaccine-preventable deaths worldwide. The aim of this study was to determine the seroprevalence of IgG antibodies to pertussis toxin (PT) and diphtheria am...
Pertussis Toxin Travel-Related Illness Africa Whooping Cough China Seroepidemiologic Studies Adult Humans Asian People Cross-Sectional Studies Antibodies, Bacterial Immunoglobulin G Male Diphtheria Young Adult Middle Aged Employment
View on PubMed DOI

CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.

Iranian journal of allergy, asthma, and immunology Dec 3, 2018
Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in animal models. This study aims to determine the immunogenicity of CbpM, CbpG and CbpL proteins of Streptococcus pneumoniae in a mice model. The genes w...
Streptococcus pneumoniae Models, Animal Pneumococcal Vaccines Female Phagocytosis Animals Recombinant Proteins Serogroup Mice Antibodies, Bacterial Vaccination Immunity, Humoral Pneumococcal Infections Mice, Inbred BALB C Bacterial Proteins
View on PubMed

Haemophilus influenzae type b (Hib) seroprevalence and current epidemiology in England and Wales.

The Journal of infection Dec 28, 2017
INTRODUCTION: The implementation of the Hib conjugate vaccine in the United Kingdom in 1992 resulted in a rapid decline in invasive Hib disease across all age groups. However, a resurgence in 2000-2002 prompted the introduction of additional control ...
Male Infant Prevalence Adolescent Cohort Studies Haemophilus influenzae type b Child, Preschool Immunization, Secondary Child Wales Humans Immunoglobulin G Antibodies, Bacterial Female Vaccines, Conjugate Risk Factors Vaccination Haemophilus Infections Seroepidemiologic Studies Haemophilus Vaccines United Kingdom
View on PubMed DOI

Antigenic and pathogenicity activities of Ralstonia solanacearum race 3 biovar 2 molecularly identified and detected by indirect ELISA using polyclonal antibodies generated in rabbits.

Microbial pathogenesis Dec 25, 2017
Eight molecular-characterized isolates of Ralstonia solanacearum from potato belonging to race 3 biovar 2, their virulence were evaluated on potato cv. Lady Rosette, tomato cv. Strain B, eggplant cv. Balady and pepper cv. Balady and showed high virul...
Ralstonia solanacearum Solanum melongena Plant Diseases Female Solanum tuberosum Antibodies, Bacterial Animals Enzyme-Linked Immunosorbent Assay Solanum lycopersicum Rabbits
View on PubMed DOI

Immunologic non-inferiority and safety of the investigational pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) 4-dose vial presentation compared to the licensed PHiD-CV 1-dose vial presentation in infants: A phase III randomized study.

Vaccine Dec 23, 2017
BACKGROUND: To support vaccination programs in developing countries, a 4-dose vial presentation of pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was developed. This study assessed immunologic non-inferiority a...
Pneumococcal Vaccines Immunization, Secondary Pneumococcal Infections Streptococcus pneumoniae Immunogenicity, Vaccine Humans Infant, Newborn Female Male Vaccination Infant Public Health Surveillance Serogroup Antibodies, Bacterial
View on PubMed DOI

Modeling protective meningococcal antibody responses and factors influencing antibody persistence following vaccination with MenAfriVac using machine learning.

PloS one Jan 1, 2025
Meningococcal meningitis poses a significant public health burden in the meningitis belt region of sub-Saharan Africa. The introduction of the meningococcal PsA-TT vaccine (MenAfriVac®) has successfully eliminated Neisseria meningitidis serogroup A (...
Adult Male Meningococcal Vaccines Adolescent Child, Preschool Antibody Formation Child Meningitis, Meningococcal Vaccination Humans Antibodies, Bacterial Machine Learning Female Young Adult
View on PubMed DOI
Popular Topics
Recent Journals