Convolutional neural networks (CNNs) have achieved remarkable accuracy in histopathology image classification, yet their decision logic remains largely opaque. Most explainability methods, such as Grad-CAM or SHAP, provide only coarse heatmaps, offer...
Journal of chemical information and modeling
Dec 17, 2025
Accurate prediction of microbe-drug associations (MDAs) is vital for guiding antimicrobial therapy and accelerating drug repositioning. Although experimental validation remains the gold standard, it is costly and time-consuming. Existing models, ofte...
Metabolites play a crucial role in sustaining biological activities and are also a significant source of new drug development. Nuclear magnetic resonance (NMR) spectroscopy is one of the most important tools for identifying the structures of the meta...
Early and reliable diagnostic tools are critical for slowing the progression of Alzheimer's disease (AD), a neurodegenerative disorder characterized by memory loss and cognitive decline. This study introduces, ViTTL, lightweight deep learning framewo...
The current gold standard for detecting epileptic seizures is in-hospital video-Electroencephalography (vEEG), but vEEG is resource-intensive and imposes considerable burdens on patients and caregivers. Wearable devices offer an alternative to monito...
BACKGROUND: Knee cartilage injury (KCI) poses significant challenges in the early clinical diagnosis process, primarily due to its high incidence, the complexity of healing, and the limited sensitivity of initial imaging modalities.
Retinal vein cannulation (RVC) is an emerging method for treating retinal vein occlusion (RVO). The success of this procedure depends on surgeon expertise and, recently, robotic assistance. This paper proposes an autonomous RVC workflow leveraging de...
Monochromatic cone beam computed tomography reconstruction algorithms are still most prominent in practice. Since the x-ray detectors of today's machines are mostly energy integrating detectors and thus not able to resolve photon energy levels, recon...
3D bioprinting enables rapid fabrication of complex biological structures for tissue engineering applications. However, optimizing bioink formulation remains challenging due to complex relationships among material properties, printability, and cell v...
The estimation of weaning duration from incremental dentine δ15N and δ13C values offers insights into health, nutrition, and demography in past populations. In this study, we developed a novel machine learning approach to estimate weaning duration us...
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