AIMC Topic: Pharmacovigilance

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Comparative safety profiling of sodium zirconate cyclosilicate and patiromer using real-world FAERS data: A pharmacovigilance analysis.

Medicine
This study aimed to detect and contrast the adverse drug event (ADE) signals associated with sodium zirconate cyclosilicate (SZC) and Patiromer by leveraging the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS), thereby in...

A review on adverse drug reaction related to medication in health sector: an account of what we have discovered and implemented-pharmacovigilance.

Naunyn-Schmiedeberg's archives of pharmacology
Despite the extensive research on medication-related adverse events (MRAEs) in healthcare, the assessment of the present scenario is made more difficult by the high degree of variability in study results. This study's primary goal was to create a cur...

Detecting Adverse Drug Events in Clinical Notes Using Large Language Models.

Studies in health technology and informatics
Monitoring adverse drug events (ADEs) is critical for pharmacovigilance and patient safety. However, identifying ADEs remains challenging, as suspected or confirmed side effects are often documented solely in the unstructured text of electronic healt...

Leveraging Generative AI for Drug Safety and Pharmacovigilance.

Current reviews in clinical and experimental pharmacology
Predictions are made by artificial intelligence, especially through machine learning, which uses algorithms and past knowledge. Notably, there has been an increase in interest in using artificial intelligence, particularly generative AI, in the pharm...

Causal Deep Learning for the Detection of Adverse Drug Reactions: Drug-Induced Acute Kidney Injury as a Case Study.

Studies in health technology and informatics
Causal Deep/Machine Learning (CDL/CML) is an emerging Artificial Intelligence (AI) paradigm. The combination of causal inference and AI could mine explainable causal relationships between data features, providing useful insights for various applicati...

Navigating the Complexities of Artificial Intelligence-Enabled Real-World Data Collection for Oncology Pharmacovigilance.

JCO clinical cancer informatics
This new editorial discusses the promise and challenges of successful integration of natural language processing methods into electronic health records for timely, robust, and fair oncology pharmacovigilance.

Current Scenario and Future Prospects of Adverse Drug Reactions (ADRs) Monitoring and Reporting Mechanisms in the Rural Areas of India.

Current drug safety
Pharmacovigilance (PV) deals with the detection, collection, assessment, understanding, and prevention of adverse effects associated with drugs. The objective of PV is to ensure the safety of the medicines and patients by monitoring and reporting all...

Overcoming Major Barriers to Build Efficient Decision Support Systems in Pharmacovigilance.

Studies in health technology and informatics
Many decision support methods and systems in pharmacovigilance are built without explicitly addressing specific challenges that jeopardize their eventual success. We describe two sets of challenges and appropriate strategies to address them. The firs...

Named Entity Recognition in Pubmed Abstracts for Pharmacovigilance Using Deep Learning.

Studies in health technology and informatics
Methods of natural language processing associated with machine learning or deep learning can support detection of adverse drug reactions in abstracts of case reports available on Pubmed. In 2012, Gurulingappa et al. proposed a training set for the re...

DeepADEMiner: a deep learning pharmacovigilance pipeline for extraction and normalization of adverse drug event mentions on Twitter.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Research on pharmacovigilance from social media data has focused on mining adverse drug events (ADEs) using annotated datasets, with publications generally focusing on 1 of 3 tasks: ADE classification, named entity recognition for identify...