AIMC Topic: Precision Medicine

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[Analysis of the Tumor Immune Microenvironment of Colorectal Cancer by Deep Learning-Based Imaging Cytometry].

Gan to kagaku ryoho. Cancer & chemotherapy
The tumor immune microenvironment(TIME)of colorectal cancer contains indicators of unique therapeutic outcomes for each cancer patient. Deep learning-based imaging cytometry(DL-IC), which can obtain objective and reproducible cell- related informatio...

[Not Available].

Recenti progressi in medicina
Advancing our understanding of complex diseases necessitates an interdisciplinary dialogue beyond artificial intelligence (AI) in the field of medicine. Two decades after the completion of the Human Genome Project, genetic sequencing has facilitated ...

MRI-derived radiomics models for diagnosis, aggressiveness, and prognosis evaluation in prostate cancer.

Journal of Zhejiang University. Science. B
Prostate cancer (PCa) is a pernicious tumor with high heterogeneity, which creates a conundrum for making a precise diagnosis and choosing an optimal treatment approach. Multiparametric magnetic resonance imaging (mp-MRI) with anatomical and function...

Deep Learning-based Image Cytometry Using a Bit-pattern Kernel-filtering Algorithm to Avoid Multi-counted Cell Determination.

Anticancer research
BACKGROUND/AIM: In pathology, the digitization of tissue slide images and the development of image analysis by deep learning have dramatically increased the amount of information obtainable from tissue slides. This advancement is anticipated to not o...

AttOmics: attention-based architecture for diagnosis and prognosis from omics data.

Bioinformatics (Oxford, England)
MOTIVATION: The increasing availability of high-throughput omics data allows for considering a new medicine centered on individual patients. Precision medicine relies on exploiting these high-throughput data with machine-learning models, especially t...

Overcoming the challenges to implementation of artificial intelligence in pathology.

Journal of the National Cancer Institute
Pathologists worldwide are facing remarkable challenges with increasing workloads and lack of time to provide consistently high-quality patient care. The application of artificial intelligence (AI) to digital whole-slide images has the potential of d...

A Review on Deep Learning-driven Drug Discovery: Strategies, Tools and Applications.

Current pharmaceutical design
It takes an average of 10-15 years to uncover and develop a new drug, and the process is incredibly time-consuming, expensive, difficult, and ineffective. In recent years the dramatic changes in the field of artificial intelligence (AI) have helped t...

Improved drug response prediction by drug target data integration via network-based profiling.

Briefings in bioinformatics
Drug response prediction (DRP) is important for precision medicine to predict how a patient would react to a drug before administration. Existing studies take the cell line transcriptome data, and the chemical structure of drugs as input and predict ...

Advancing the precision management of inflammatory bowel disease in the era of omics approaches and new technology.

World journal of gastroenterology
There is great heterogeneity among inflammatory bowel disease (IBD) patients in terms of pathogenesis, clinical manifestation, response to treatment, and prognosis, which requires the individualized and precision management of patients. Many studies ...