One important aspect of precision medicine aims to deliver the right medicine to the right patient at the right dose at the right time based on the unique 'omics' features of each individual patient, thus maximizing drug efficacy and minimizing adver...
Advances in experimental medicine and biology
Jan 1, 2019
Scientific findings over the past few decades have shaped our understanding of the underlying neurobiology associated with psychiatric illnesses. However, despite significant advances in research, there is widespread disappointment with the overall p...
An increasing trend in funding towards artificial intelligence (AI) research in medicine has re-animated huge expectations for future applications. Obstetrics and gynaecology remain highly litigious specialities, accounting for a large proportion of ...
The development of high-throughput, data-intensive biomedical research assays and technologies has created a need for researchers to develop strategies for analyzing, integrating, and interpreting the massive amounts of data they generate. Although a...
Studies in health technology and informatics
Jan 1, 2019
The paper introduces a structured approach to transforming healthcare towards personalized, preventive, predictive, participative precision (P5) medicine. It highlights the promising methodological paradigm changes, accompanied by related organizatio...
Many new technologies based on computer technologies which are very successful in industry spread over the medicine and became integral part of all its disciplines. Artificial intelligence opened new possibilities for managing and solving many proble...
This review critically analyzes how machine learning is being used to support clinical decision-making in the management of potentially resectable pancreatic cancer. Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses...
Database : the journal of biological databases and curation
Jan 1, 2019
Gastrointestinal (GI) cancer is common, characterized by high mortality, and includes oesophagus, gastric, liver, bile duct, pancreas, rectal and colon cancers. The insufficient specificity and sensitivity of biomarkers is still a key clinical hindra...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2019
Cancer is a complex collection of diseases that are to some degree unique to each patient. Precision oncology aims to identify the best drug treatment regime using molecular data on tumor samples. While omics-level data is becoming more widely availa...
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