AIMC Topic: Probability

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[Shared decision-making in metaclinical medicine: from informed consent to shared probability].

Giornale italiano di cardiologia (2006)
At the dawn of "metaclinical medicine" era, shared decision-making represents the overcoming of modern medicine guidelines and classical medicine experience. The patient's life plan, the doctor's health plan, the scientist's evidence-based plan, the ...

An online framework for survival analysis: reframing Cox proportional hazards model for large data sets and neural networks.

Biostatistics (Oxford, England)
In many biomedical applications, outcome is measured as a "time-to-event" (e.g., disease progression or death). To assess the connection between features of a patient and this outcome, it is common to assume a proportional hazards model and fit a pro...

ActivePPI: quantifying protein-protein interaction network activity with Markov random fields.

Bioinformatics (Oxford, England)
MOTIVATION: Protein-protein interactions (PPI) are crucial components of the biomolecular networks that enable cells to function. Biological experiments have identified a large number of PPI, and these interactions are stored in knowledge bases. Howe...

The Deep Generative Decoder: MAP estimation of representations improves modelling of single-cell RNA data.

Bioinformatics (Oxford, England)
MOTIVATION: Learning low-dimensional representations of single-cell transcriptomics has become instrumental to its downstream analysis. The state of the art is currently represented by neural network models, such as variational autoencoders, which us...

One T Gate Makes Distribution Learning Hard.

Physical review letters
The task of learning a probability distribution from samples is ubiquitous across the natural sciences. The output distributions of local quantum circuits are of central importance in both quantum advantage proposals and a variety of quantum machine ...

Artificial intelligence chatbots will revolutionize how cancer patients access information: ChatGPT represents a paradigm-shift.

JNCI cancer spectrum
On November 30, 2022, OpenAI enabled public access to ChatGPT, a next-generation artificial intelligence with a highly sophisticated ability to write, solve coding issues, and answer questions. This communication draws attention to the prospect that ...

Digitally predicting protein localization and manipulating protein activity in fluorescence images using 4D reslicing GAN.

Bioinformatics (Oxford, England)
MOTIVATION: While multi-channel fluorescence microscopy is a vital imaging method in biological studies, the number of channels that can be imaged simultaneously is limited by technical and hardware limitations such as emission spectra cross-talk. On...

Embryologist agreement when assessing blastocyst implantation probability: is data-driven prediction the solution to embryo assessment subjectivity?

Human reproduction (Oxford, England)
STUDY QUESTION: What is the accuracy and agreement of embryologists when assessing the implantation probability of blastocysts using time-lapse imaging (TLI), and can it be improved with a data-driven algorithm?

BITES: balanced individual treatment effect for survival data.

Bioinformatics (Oxford, England)
MOTIVATION: Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatmen...

Survival prediction model for right-censored data based on improved composite quantile regression neural network.

Mathematical biosciences and engineering : MBE
With the development of the field of survival analysis, statistical inference of right-censored data is of great importance for the study of medical diagnosis. In this study, a right-censored data survival prediction model based on an improved compos...