AIMC Topic: Prostatic Neoplasms

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Using AI to triage patients without clinically significant prostate cancer using biparametric MRI and PSA.

Abdominal radiology (New York)
OBJECTIVES: To train and evaluate the performance of a machine learning triaging tool that identifies MRI negative for clinically significant prostate cancer and to compare this against non-MRI models.

Research-based clinical deployment of artificial intelligence algorithm for prostate MRI.

Abdominal radiology (New York)
PURPOSE: A critical limitation to deployment and utilization of Artificial Intelligence (AI) algorithms in radiology practice is the actual integration of algorithms directly into the clinical Picture Archiving and Communications Systems (PACS). Here...

Pix2Pix generative-adversarial network in improving the quality of T2-weighted prostate magnetic resonance imaging: a multi-reader study.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: To assess the performance and feasibility of generative deep learning in enhancing the image quality of T2-weighted (T2W) prostate magnetic resonance imaging (MRI).

In Silico Digital Twins of Bone Metastasis Enable Investigation of Tumor Progression and Therapy Response.

Cancer research
UNLABELLED: Bone metastasis (BM) is a leading cause of morbidity and mortality in patients with prostate and renal cancer. The complex and dynamic biological processes driving its progression present significant challenges for both understanding and ...

A Neighbor-Sensitive Multi-Modal Flexible Learning Framework for Improved Prostate Tumor Segmentation in Anisotropic MR Images.

IEEE transactions on bio-medical engineering
Accurate segmentation of prostate tumors from multi-modal magnetic resonance (MR) images is crucial for the diagnosis and treatment of prostate cancer. However, the robustness of existing segmentation methods is limited, mainly because these methods ...

Development of AI-integrated smartphone sponge-based sensors utilizing His@Co-NC nanozymes for highly sensitive sarcosine detection.

Biosensors & bioelectronics
The increasing demand for point-of-care detection of low-concentration cancer biomarkers has necessitated the development of innovative nanozyme-based sensing technologies. Here, a smartphone-integrated platform is presented that utilizes artificial ...

Analysis and characterization of extrachromosomal circular DNA in prostate cancer: Potential biomarker discovery from urine, plasma, and tumor samples.

Cancer letters
Extrachromosomal circular DNA (eccDNA) may contribute to genomic rearrangements and tumor heterogeneity, playing a role in cancer development and progression. This study evaluates eccDNA as a biomarker for prostate cancer by characterizing its profil...

Single- versus multi-model in the deep learning prediction of monitor units per control point for automated treatment planning in prostate cancer.

Journal of applied clinical medical physics
BACKGROUND: In contemporary radiation therapy, the radiation is modulated to conform the prescription dose to the tumor and spare organs at risk. The modulation results from a complex mathematical calculation that requires several iterations to reach...

Impact of deep learning model uncertainty on manual corrections to MRI-based auto-segmentation in prostate cancer radiotherapy.

Journal of applied clinical medical physics
BACKGROUND: Deep learning (DL)-based organ segmentation is increasingly used in radiotherapy. While methods exist to generate voxel-wise uncertainty maps from DL-based auto-segmentation models, these maps are rarely presented to clinicians.