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Radiotherapy, Intensity-Modulated

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Improvement of deep learning prediction model in patient-specific QA for VMAT with MLC leaf position map and patient's dose distribution.

Journal of applied clinical medical physics
PURPOSE: Deep learning-based virtual patient-specific quality assurance (QA) is a novel technique that enables patient QA without measurement. However, this method could be improved by further evaluating the optimal data to be used as input. Therefor...

Deep learning-based markerless lung tumor tracking in stereotactic radiotherapy using Siamese networks.

Medical physics
BACKGROUND: Radiotherapy (RT) is involved in about 50% of all cancer patients, making it a very important treatment modality. The most common type of RT is external beam RT, which consists of delivering the radiation to the tumor from outside the bod...

Comprehensive dose evaluation of a Deep Learning based synthetic Computed Tomography algorithm for pelvic Magnetic Resonance-only radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Magnetic Resonance (MR)-only radiotherapy enables the use of MR without the uncertainty of MR-Computed Tomography (CT) registration. This requires a synthetic CT (sCT) for dose calculations, which can be facilitated by a novel...

Patient selection for proton therapy using Normal Tissue Complication Probability with deep learning dose prediction for oropharyngeal cancer.

Medical physics
BACKGROUND: In cancer care, determining the most beneficial treatment technique is a key decision affecting the patient's survival and quality of life. Patient selection for proton therapy (PT) over conventional radiotherapy (XT) currently entails co...

A comparative study of deep learning-based knowledge-based planning methods for 3D dose distribution prediction of head and neck.

Journal of applied clinical medical physics
PURPOSE: In this paper, we compare four novel knowledge-based planning (KBP) algorithms using deep learning to predict three-dimensional (3D) dose distributions of head and neck plans using the same patients' dataset and quantitative assessment metri...

Implementation and evaluation of an intelligent automatic treatment planning robot for prostate cancer stereotactic body radiation therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: We previously developed a virtual treatment planner (VTP), an artificial intelligence robot, operating a treatment planning system (TPS). Using deep reinforcement learning guided by human knowledge, we trained the VTP to autonomously adjust ...

A deep learning-based approach for statistical robustness evaluation in proton therapy treatment planning: a feasibility study.

Physics in medicine and biology
. Robustness evaluation is critical in particle radiotherapy due to its susceptibility to uncertainties. However, the customary method for robustness evaluation only considers a few uncertainty scenarios, which are insufficient to provide a consisten...

TrDosePred: A deep learning dose prediction algorithm based on transformers for head and neck cancer radiotherapy.

Journal of applied clinical medical physics
BACKGROUND: Intensity-Modulated Radiation Therapy (IMRT) has been the standard of care for many types of tumors. However, treatment planning for IMRT is a time-consuming and labor-intensive process.

Patient-specific three-dimensional dose distribution prediction via deep learning for prostate cancer therapy: Improvement with the structure loss.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Deep learning (DL)-based dose distribution prediction can potentially reduce the cost of inverse planning process. We developed and introduced a structure-focused loss (L) for 3D dose prediction to improve prediction accuracy. This study inv...

A novel mathematical model to generate semi-automated optimal IMRT treatment plan based on predicted 3D dose distribution and prescribed dose.

Medical physics
BACKGROUND: In recent years, with the development of artificial intelligence and deep learning techniques, it has become possible to predict the three-dimensional distribution dose (3D ) of a new patient based on the treatment plans of similar recent...